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Strawberry Powder for Memory and Mobility in Obese Older Adults


This study will test the effects of strawberry powder on cognition and mobility in cognitively normal obese older adults.

Minimum Age Maximum Age Gender Healthy Volunteers
55 Years 75 Years All Yes
October 1, 2017
March 1, 2021

  • Body mass index of 30 to 40
  • Hemoglobin A1C level between 5.7% and 6.4%
  • Height between 60 and 74 inches tall
  • Adequate visual ability to read and perform computer tasks
  • Speak and write English
  • Ability to walk independently for 20 minutes
  • Postmenopausal (absence of menstruation for at least 12 months or bilateral oophorectomy)
  • Willing to abstain from recreational drug use

  • Vegetarian or vegan
  • Cognitive impairment, memory loss, or neurological or psychological disorder that interferes with activities of daily living
  • Muscle or mobility deficit that would interfere with walking independently for 20 minutes
  • Chronic conditions associated with increased risk of falls or falls within the last year not related to unusual circumstances, such as slipping on ice or being pushed
  • Gastrointestinal diseases, conditions, or medications influencing gastrointestinal absorption
  • Use of medications or dietary supplements known or suspected to influence study outcomes
  • Mini-Mental State Examination score of less than 24
  • Diagnosis of diabetes mellitus, fasting glucose level of 126 mg/dL or higher, or taking diabetes medication
  • Liver dysfunction, history of cirrhosis, or elevated SGPT, SGOT, or total bilirubin levels
  • Kidney disease as indicated by serum creatinine level higher than 1.5 mg/dL
  • Uncontrolled blood pressure
  • Heart or lung conditions that limit ability to walk or result in difficult or labored breathing
  • Allergy to strawberry or ingredients in the placebo
  • More than 2 servings per day of beer (12 ounces), wine (5 ounces), or liquor (1.5 ounces)
  • Recent inflammatory diseases, such as rheumatoid arthritis or lupus
  • Cigarette smoking, use of nicotine replacement products, or smoking of marijuana/consumption of edibles in past 3 months or during study
  • History of stomach or bowel resection (other than appendectomy), gastric bypass or other bariatric weight-loss procedure
  • Cancer (except for non-melanoma skin cancer) in past 3 years or actively using cancer chemotherapeutic agents
  • Clotting/bleeding disorders or ongoing anticoagulant use
  • Bilateral mastectomy with nodal dissection
  • No Social Security number (unable to pay stipend)
  • Blood biochemistries outside of normal range
  • Prior participation in a study involving berry supplementation at the institution

Participants will be randomly assigned to consume either 12 grams of freeze-dried strawberry powder or placebo 2 times a day with water for 3 months. Participants will complete cognitive, lifestyle, and mobility tests including a virtual navigation task and a gait speed testmeasuring the time it takes to walk a specified distanceusing a treadmill.

Name City State Zip Status Primary Contact
Tammy M Scott
Boston Massachusetts 02111 Recruiting Tammy M Scott, PhD

USDA Human Nutrition Research Center on Aging

  • California Strawberry Commission

Name Role Affiliation
Tammy M. Scott, PhD Principal Investigator Tufts University
Barbara Shukitt-Hale, PhD Principal Investigator USDA Human Nutrition Research Center on Aging

Name Phone Email
Kimberly Dupiton 617-556-3012


The Effects of Strawberry Supplementation on Memory and Gait Among Over-weight Older Adults