Strawberry Powder for Memory and Mobility in Obese Older Adults
This study will test the effects of strawberry powder on cognition and mobility in cognitively normal obese older adults.
|Minimum Age||Maximum Age||Gender||Healthy Volunteers|
|55 Years||75 Years||All||Yes|
- Body mass index of 30 to 40
- Hemoglobin A1C level between 5.7% and 6.4%
- Height between 60 and 74 inches tall
- Adequate visual ability to read and perform computer tasks
- Speak and write English
- Ability to walk independently for 20 minutes
- Postmenopausal (absence of menstruation for at least 12 months or bilateral oophorectomy)
- Willing to abstain from recreational drug use
- Vegetarian or vegan
- Cognitive impairment, memory loss, or neurological or psychological disorder that interferes with activities of daily living
- Muscle or mobility deficit that would interfere with walking independently for 20 minutes
- Chronic conditions associated with increased risk of falls or falls within the last year not related to unusual circumstances, such as slipping on ice or being pushed
- Gastrointestinal diseases, conditions, or medications influencing gastrointestinal absorption
- Use of medications or dietary supplements known or suspected to influence study outcomes
- Mini-Mental State Examination score of less than 24
- Diagnosis of diabetes mellitus, fasting glucose level of 126 mg/dL or higher, or taking diabetes medication
- Liver dysfunction, history of cirrhosis, or elevated SGPT, SGOT, or total bilirubin levels
- Kidney disease as indicated by serum creatinine level higher than 1.5 mg/dL
- Uncontrolled blood pressure
- Heart or lung conditions that limit ability to walk or result in difficult or labored breathing
- Allergy to strawberry or ingredients in the placebo
- More than 2 servings per day of beer (12 ounces), wine (5 ounces), or liquor (1.5 ounces)
- Recent inflammatory diseases, such as rheumatoid arthritis or lupus
- Cigarette smoking, use of nicotine replacement products, or smoking of marijuana/consumption of edibles in past 3 months or during study
- History of stomach or bowel resection (other than appendectomy), gastric bypass or other bariatric weight-loss procedure
- Cancer (except for non-melanoma skin cancer) in past 3 years or actively using cancer chemotherapeutic agents
- Clotting/bleeding disorders or ongoing anticoagulant use
- Bilateral mastectomy with nodal dissection
- No Social Security number (unable to pay stipend)
- Blood biochemistries outside of normal range
- Prior participation in a study involving berry supplementation at the institution
Participants will be randomly assigned to consume either 12 grams of freeze-dried strawberry powder or placebo 2 times a day with water for 3 months. Participants will complete cognitive, lifestyle, and mobility tests including a virtual navigation task and a gait speed testmeasuring the time it takes to walk a specified distanceusing a treadmill.
Tammy M Scott
Tammy M Scott, PhD
USDA Human Nutrition Research Center on Aging
- California Strawberry Commission
|Tammy M. Scott, PhD||Principal Investigator||Tufts University|
|Barbara Shukitt-Hale, PhD||Principal Investigator||USDA Human Nutrition Research Center on Aging|
The Effects of Strawberry Supplementation on Memory and Gait Among Over-weight Older Adults
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