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Social Dancing Movement Intervention for Memory Enhancement (MIME)

Recruiting

This pilot study will test social dancing as a method to prevent or delay cognitive decline in older adults at high risk for Alzheimer's disease and related dementias.

Minimum Age Maximum Age Gender Healthy Volunteers
65 Years N/A All Yes
March 28, 2019
August 31, 2020
32

  • A score of 6 on the Memory Impairment Screen or 1 on the AD-8
  • Plan to live in the area for next year or more
  • English speaking
  • Willing to complete a functional magnetic resonance imaging (MRI) scan

  • Diagnosis of dementia (previously or at initial visit)
  • Serious chronic or acute illness such as cancer (late-stage, metastatic, or on active treatment), chronic pulmonary disease on ventilator or continuous oxygen therapy, or active liver disease
  • Mobility limitations due to musculoskeletal or cardiovascular conditions that prevent dancing
  • Any medical condition or chronic medication use that will compromise safety or affect cognitive functioning (e.g., antipsychotics)
  • Terminal illness with life expectancy less than a year
  • Presence of progressive, degenerative neurologic disease (e.g., Parkinson's disease or amyotrophic lateral sclerosis)
  • Severe auditory or visual loss
  • Active psychoses or psychiatric symptoms (such as agitation) noted during the clinic visit that will prevent study completion
  • Participation in competitive or recreational dancing more than once a month for the past 6 months
  • Participation in another interventional study that overlaps with this study

Participants will be randomly assigned to either social dancing or the comparison activity, treadmill walking, for 90-minute sessions twice weekly for 6 months. Social dances will include the fox-trot, waltz, and Latin dances. Both groups will have warm-up and cool-down periods. Researchers will measure changes in executive function, including memory, processing speed, and attention.

Name City State Zip Status Primary Contact
Albert Einstein College of Medicine
Bronx New York 10461 Recruiting Emmeline Ayers, MPH
718-430-3835
emmeline.ayers@einstein.yu.edu

Albert Einstein College of Medicine

  • National Institute on Aging (NIA)

Name Role Affiliation
Joe Verghese, MBBS Principal Investigator Albert Einstein College of Medicine
Helena Blumen, PhD Principal Investigator Albert Einstein College of Medicine

Name Phone Email
Joe Verghese, MBBS 718-430-3877 joe.verghese@einstein.yu.edu
Helena Blumen, PhD 718-430-3810 helena.blumen@einstein.yu.edu

NCT03475316

Social Dancing Intervention for Older Adults at High Risk of Alzheimer's Disease and Other Dementias: A Pilot Study.