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Sleep Intervention for People with Alzheimer's Disease and their Caregivers

Recruiting

Studies consistently show the negative health impact of sleep problems in both people with Alzheimer's disease and their caregivers. This study aims to develop a sleep intervention program specifically tailored for these caregiver/care recipient pairs.

Minimum Age Maximum Age Gender Healthy Volunteers
60 Years N/A All No
September 11, 2018
April 30, 2022
80

Participants with Alzheimer's

  • Diagnosis of Alzheimer's disease or probable or possible Alzheimer's, based on Mini Mental State Exam score >12 and neuroimaging evidence
  • Community-dwelling
  • More than one sleep problem occurring more than three times per week

Caregivers

  • Live with an eligible participant with Alzheimer's
  • Regularly assist person with more than one activity of daily living for the past 6 months (i.e., bathing, dressing, toileting, transfers, continence, feeding) or more than one Instrumental activity of daily living (i.e., using the telephone, shopping, preparing meals, housekeeping, laundry, transportation, taking medicine, managing money)
  • Pittsburgh Sleep Quality Index total score >5
  • Montreal Cognitive Assessment score of 23 or higher
  • English speaking

  • Person with Alzheimer's is bed-bound

Nighttime sleep disturbance in people with Alzheimer's is associated with shorter survival, lower quality of life, and decreased social engagement. Poor sleep in their caregivers is associated with increased depression, higher caregiver burden, and increased inflammation. Behavioral sleep interventions for community-dwelling caregivers and care recipients are needed to test effects on sleep and other health outcomes.

In this study, one group of caregivers will receive information about sleep, aging, and dementia, but without specific or individualized recommendations. The other group will receive sleep hygiene recommendations and a behavioral sleep intervention. The groups will be compared in terms of changes in sleep efficiency and quality and any impact on care recipient behaviors and caregiver depression and stress.

The sleep program involves four face-to-face meetings plus one telephone session. A unique aspect of the proposed study is that the program is tailored to address sleep problems of both patients and caregivers.

Name City State Zip Status Primary Contact
University of California Los Angeles
Los Angeles California 90095 Recruiting Yeonsu Song, PhD

Veterans Affairs Greater Los Angeles Healthcare System
North Hills California 91343 Recruiting Yeonsu Song, PhD
818-891-7711

University of California, Los Angeles

Name Role Affiliation
Yeonsu Song, PhD Principal Investigator University of California, Los Angeles

Name Phone Email
Yeonsu Song, PhD 818-891-7711 YeonsuSong@mednet.ucla.edu

NCT03455569

A Dyadic Sleep Intervention for Alzheimer's Disease Patients and Their Caregivers