Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI)
Dementia is considered to be present when a person can no longer handle complex activities of daily living, such as managing finances. This study will investigate the relationship between changes in the ability to handle finances and brain perfusion (blood flow in the brain), as measured by arterial spin-labeling MRI. Subjects will also undergo neuropsychological tests focusing on several types of memory and thought processes, with special emphasis on semantic memory. The study will examine whether changes in financial capacity are better predicted by neuropsychological tests or the brain scan.
|Minimum Age||Maximum Age||Gender||Healthy Volunteers|
|50 Years||89 Years||Both||Accepts Healthy Volunteers|
++Normal cognition or memory impairment (MCI or mild Alzheimer's disease)++English speaking++Right handed++Adequate vision and hearing to take part in tests++Able and willing to undergo MRI scan++Medically and psychiatrically stable
++Brain disease (such as tumor, Parkinson's disease, major stroke)++Pregnancy++Inability to tolerate MRI (due to metal in body or claustrophobia)
Birmingham VA Medical Center, Birmingham, AL
Semantic Memory, Financial Capacity and Brain Perfusion in MCI