Find Alzheimer’s Disease and Related Clinical Trials
Search for clinical trials and studies related to Alzheimer's, other dementias, mild cognitive impairment, and caregiving.
Results found: 66
Purpose: To identify reliable methods for tracking corticobasal degeneration and progressive supranuclear palsy.
Purpose: To examine the impact of a combined cognitive training and aerobic exercise intervention in sedentary older adults.
Purpose: To compare two intervention strategies for reducing emotional and cardiovascular disease risk in Alzheimer's caregivers.
Purpose: To determine the relationships among clinical, cognitive, imaging, genetic, and biomarker characteristics of the entire spectrum of Alzheimer's disease.
Purpose: To enroll individuals who are interested in learning about and possibly participating in Alzheimer's prevention clinical studies and trials in a national registry.
Purpose: To register people into an online research tool aimed at accelerating enrollment into Alzheimer's clinical trials by identifying and tracking individuals who may be at higher risk for developing the disease.
Purpose: To test the effects of different kinds of auditory training on hearing function in healthy adults.
Purpose: To compare the impact of a walking program, computer-based cognitive training program, and both programs in adults with mild cognitive impairment.
Purpose: To evaluate a brain fitness intervention for improving cognitive health in middle-aged and older adults.
Purpose: To test the safety and action of the drug bisnorcymserine in healthy older volunteers.
Purpose: To study brain changes in veterans with traumatic brain injury or post traumatic stress disorder, with and without mild cognitive impairment.
Purpose: To compare the brain's removal of waste after a good night's sleep and after sleep deprivation.
Purpose: To enroll people interested in participating in brain health research in an ongoing online registry.
Purpose: To test whether two investigational drugs, CAD106 and CNP520, can prevent or delay Alzheimer's symptoms in people at high risk.
Purpose: To determine the effects of citicoline on cognitive performance in healthy adults with age-associated memory impairment.
Purpose: To determine the safety and effects of CNP520 in cognitively normal older adults who are at risk for Alzheimer's disease.
Purpose: To validate several novel cognitive tasks and correlate them with Alzheimer's disease biomarkers in people who are cogntitively normal or have mild cognitive impairment.
Purpose: To evaluate the effects of cognitive rehabilitation and transcranial electrical stimulation in adults who are cognitively normal or experiencing cognitive dysfunction.
Purpose: To examine the potential benefits of a combination of at-home cognitive training and Trintellix® on cognition in older adults with age-related cognitive decline.
Purpose: To test whether cognitive training can help decrease falls in older adults who are at risk for falls.
Purpose: To examine changes in brain function as a result of cognitive training in older adults with and without mild cognitive impairment.
Purpose: To examine the impact on older adults of learning the results of amyloid brain imaging.
Purpose: To assess the safety and tolerability of the investigational drug COR388 in healthy older adults and those with Alzheimer's disease.
Purpose: To compare Alzheimer's disease caregiving in the United States and Mexico.
Purpose: To study the effects of an education and skill-building intervention on family caregivers of veterans with dementia.
Purpose: To assess the effect of a cocoa-derived dietary supplement on cognitive function related to the dentate gyrus.
Purpose: To test how different types of meals affect Alzheimer's biomarkers in healthy older adults with and without the APOE E4 genotype.
Purpose: To explore the effect of dietary ketosis on adults with early-stage memory loss and metabolic syndrome.
Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Purpose: To assess the safety, tolerability, and biomarker efficacy of gantenerumab and solanezumab in individuals who have a genetic mutation for autosomal-dominant Alzheimer's disease.
Purpose: To determine if the drug memantine can improve learning and memory in adolescents and young adults with Down syndrome.
Purpose: To evaluate the safety, tolerability, and pharmacodynamics of E2027 in healthy participants.
Purpose: To test training for care partners and people with early-stage memory loss or dementia to reduce stress and increase well-being and quality of life.
Purpose: To examine the sensitivity of functional MRI to detect brain changes in healthy older adults at genetic risk for Alzheimer's disease who take donepezil (Aricept).
Purpose: To identify people interested in participating in research studies or clinical trials based in part on their genetic background.
Purpose: To learn more about biomarkers and their relationship to aging.
Purpose: To learn more about the genetic causes of movement disorders and dementias.
Purpose: To evaluate the safety and pharmacokinetics of a transdermal donepezil patch applied to different body locations on healthy volunteers.
Purpose: To test the use of mobile health devices in helping older adults independently walk to improve cognitive health.
Purpose: To examine cognitive and neural biomarkers in adults who are overweight or obese and younger than 50.
Purpose: To evaluate the effect of exercise and healthy living education on brain health, cognition, and physical function in older adults with cognitive concerns.
Purpose: To learn about thinking and behavior in families in which one or more relatives has a genetic mutation associated with frontotemporal dementia.
Purpose: To evaluate the feasibility of a Mediterranean diet in older adults.
Purpose: To determine if following a Mediterranean diet resulting in weight loss improves cognition in obese older adults.
Purpose: To evaluate a diet and lifestyle intervention on methylation-related biomarkers in healthy older adult men.
Purpose: To study how women undergoing breast cancer treatment may develop brain changes related to the development of mild cognitive impairment.
Purpose: To test the effects of the MIND diet on cognitive decline in seniors without cognitive impairment.
Purpose: To study how genetics influences memory by analyzing adults' performance on a web-based memory test.
Purpose: To examine the effects on age-related cognitive decline of mindfulness-based stress reduction, aerobic exercise, and their combination, compared with a health discussion group.
Purpose: To evaluate the safety, tolerability, and action of the experimental drug NDX-1017 in healthy volunteers and adults with mild Alzheimer's disease.
Purpose: To develop and evaluate biomarkers using a non-invasive imaging test in people with mild cognitive impairment (MCI) or Alzheimer's.
Purpose: To evaluate the effect of icosapent ethyl in veterans at increased risk of Alzheimer's.
Purpose: To compare brain-wave patterns in older patients who have memory and thinking problems after surgery with brain-wave patterns in patients without such problems.
Purpose: To assess the effect on cognition of increasing physical activity using a body-worn sensor in older adults.
Purpose: To develop and evaluate a program to increase physical activity and improve cognitive function in African-American older adults who are sedentary.
Purpose: To test the effects of transcranial direct current stimulation on memory in people with mild cognitive impairment.
Purpose: To use magnetic resonance imaging to investigate brain function and connections in healthy adults.
Purpose: To evaluate a program for decreasing caregiver distress and strain after transitioning a cognitively impaired relative to long-term care.
Purpose: To establish a bank of blood, cerebrospinal fluid, imaging, and clinical data to be used in Alzheimer's disease research.
Purpose: To examine the role of a subset of receptors in the brain, called the nicotinic system, in memory and thinking and healthy aging.
Purpose: To study memory and aging in healthy older adults.
Purpose: To test the effects of strawberry powder on cognition and mobility in cognitively normal obese older adults.
Purpose: To test an Internet-based education program for dementia caregivers.
Purpose: To investigate the effect of transcranial alternating current stimulation on sleep and cognitive performance in older adults.
Purpose: To study the pharmacokinetics and effects of VU319 in healthy adults.