Find Alzheimer’s Disease and Related Clinical Trials
Search for clinical trials and studies related to Alzheimer's, other dementias, mild cognitive impairment, and caregiving.
Results found: 67
Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Purpose: To evaluate the effect of icosapent ethyl in veterans at increased risk of Alzheimer's.
Purpose: To compare two intervention strategies for reducing emotional and cardiovascular disease risk in Alzheimer's caregivers.
Purpose: To learn more about biomarkers and their relationship to aging.
Purpose: To learn about thinking and behavior in families in which one or more relatives has a genetic mutation associated with frontotemporal dementia.
Purpose: To identify people interested in participating in research studies or clinical trials based in part on their genetic background.
Purpose: To compare brain-wave patterns in older patients who have memory and thinking problems after surgery with brain-wave patterns in patients without such problems.
Purpose: To validate several novel cognitive tasks and correlate them with Alzheimer's disease biomarkers in people who are cogntitively normal or have mild cognitive impairment.
Purpose: To examine the effects on age-related cognitive decline of mindfulness-based stress reduction, aerobic exercise, and their combination, compared with a health discussion group.
Purpose: To establish a bank of blood, cerebrospinal fluid, imaging, and clinical data to be used in Alzheimer's disease research.
Purpose: To evaluate the safety, tolerability, and pharmacodynamics of E2027 in healthy participants.
Purpose: To identify reliable methods for tracking corticobasal degeneration and progressive supranuclear palsy.
Purpose: To examine the impact on older adults of learning the results of amyloid brain imaging.
Purpose: To compare the impact of a walking program, computer-based cognitive training program, and both programs in adults with mild cognitive impairment.
Purpose: To examine cognitive and neural biomarkers in adults who are overweight or obese and younger than 50.
Purpose: To test the use of mobile health devices in helping older adults independently walk to improve cognitive health.
Purpose: To test an Internet-based education program for dementia caregivers.
Purpose: To use magnetic resonance imaging to investigate brain function and connections in healthy adults.
Purpose: To evaluate a program for decreasing caregiver distress and strain after transitioning a cognitively impaired relative to long-term care.
Purpose: To test how different types of meals affect Alzheimer's biomarkers in healthy older adults with and without the APOE E4 genotype.
Purpose: To evaluate the effects of cognitive rehabilitation and transcranial electrical stimulation in adults who are cognitively normal or experiencing cognitive dysfunction.
Purpose: To evaluate the effect of exercise and healthy living education on brain health, cognition, and physical function in older adults with cognitive concerns.
Purpose: To investigate the effect of transcranial alternating current stimulation on sleep and cognitive performance in older adults.
Purpose: To determine if following a Mediterranean diet resulting in weight loss improves cognition in obese older adults.
Purpose: To examine the potential benefits of a combination of at-home cognitive training and Trintellix® on cognition in older adults with age-related cognitive decline.
Purpose: To determine the effects of citicoline on cognitive performance in healthy adults with age-associated memory impairment.
Purpose: To test training for care partners and people with early-stage memory loss or dementia to reduce stress and increase well-being and quality of life.
Purpose: To examine the role of a subset of receptors in the brain, called the nicotinic system, in memory and thinking and healthy aging.
Purpose: To evaluate a brain fitness intervention for improving cognitive health in middle-aged and older adults.
Purpose: To test the effects of strawberry powder on cognition and mobility in cognitively normal obese older adults.
Purpose: To enroll individuals who are interested in learning about and possibly participating in Alzheimer's prevention clinical studies and trials in a national registry.
Purpose: To evaluate the safety and tolerability of BIIB076 in cognitively normal older adults and older adults with Alzheimer's disease.
Purpose: To test the effects of transcranial direct current stimulation on memory in people with mild cognitive impairment.
Purpose: To study the effects of an education and skill-building intervention on family caregivers of veterans with dementia.
Purpose: To learn more about the genetic causes of movement disorders and dementias.
Purpose: To evaluate a diet and lifestyle intervention on methylation-related biomarkers in healthy older adult men.
Purpose: To examine the sensitivity of functional MRI to detect brain changes in healthy older adults at genetic risk for Alzheimer's disease who take donepezil (Aricept).
Purpose: To enroll people interested in participating in brain health research in an ongoing online registry.
Purpose: To study how genetics influences memory by analyzing adults' performance on a web-based memory test.
Purpose: To study memory and aging in healthy older adults.
Purpose: To study brain changes in veterans with traumatic brain injury or post traumatic stress disorder, with and without mild cognitive impairment.
Purpose: To determine the relationships among clinical, cognitive, imaging, genetic, and biomarker characteristics of the entire spectrum of Alzheimer's disease.
Purpose: To compare Alzheimer's disease caregiving in the United States and Mexico.
Purpose: To assess the effect on cognition of increasing physical activity using a body-worn sensor in older adults.
Purpose: To study the pharmacokinetics and effects of VU319 in healthy adults.
Purpose: To determine the safety and effects of CNP520 in cognitively normal older adults who are at risk for Alzheimer's disease.
Purpose: To evaluate the safety, tolerability, and action of the experimental drug NDX-1017 in healthy volunteers and adults with mild Alzheimer's disease.
Purpose: To examine changes in brain function as a result of cognitive training in older adults with and without mild cognitive impairment.
Purpose: To explore the effect of dietary ketosis on adults with early-stage memory loss and metabolic syndrome.
Purpose: To test the effects of different kinds of auditory training on hearing function in healthy adults.
Purpose: To develop and evaluate a program to increase physical activity and improve cognitive function in African-American older adults who are sedentary.
Purpose: To study how women undergoing breast cancer treatment may develop brain changes related to the development of mild cognitive impairment.
Purpose:To better understand the relationship between APOE genotype and metabolism by testing metabolic rate at rest and during a cognitive challenge in healthy adults.
Purpose: To test whether music training can stave off cognitive decline in older adults with and without mild cognitive impairment.
Purpose: To examine whether a 12-month exercise intervention improves brain health in cognitively normal older adults.
Purpose: To look at disease progression in adults with early-onset Alzheimer's disease.
Purpose: To determine if lowering blood pressure using antihypertensive drugs alters brain pulsatility, a measure of blood flow, and reduces beta-amyloid accumulation in the brains of cognitively normal older adults.
Purpose: To promote use of compensation strategies and organization systems and increased engagement with brain health activities in older adults with memory concerns.
Purpose: To examine whether increasing social interaction through face-to-face Web-based conversations could improve cognitive function in older adults who are socially isolated.
Purpose: To use positron emission tomography imaging with a new radioactive tracer 18F-MK-6240 to understand the cognitive and behavioral outcomes of tau deposition in specific brain regions in cognitively normal and mildly cognitively impaired older adults.
Purpose: To increase patient and caregiver engagement in research by gathering insights through regular surveys.
Purpose: To test the safety and action of the drug bisnorcymserine in healthy older volunteers.
Purpose: To assess the safety and tolerability of the investigational drug COR388 in healthy older adults and those with Alzheimer's disease.
Purpose: To determine if the drug memantine can improve learning and memory in adolescents and young adults with Down syndrome.
Purpose: To examine the impact of a combined cognitive training and aerobic exercise intervention in sedentary older adults.
Purpose: To test whether cognitive training can help decrease falls in older adults who are at risk for falls.
Purpose: To test whether two investigational drugs, CAD106 and CNP520, can prevent or delay Alzheimer's symptoms in people at high risk.