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Find Alzheimer’s Disease and Related Clinical Trials

Search for clinical trials and studies related to Alzheimer's, other dementias, mild cognitive impairment, and caregiving.

Clinical Trials Search Results

Results found: 16

Aerobic Exercise and Cognitive Training for MCI (ACT Trial)

Purpose: To test the combined effects of aerobic exercise and cognitive training on cognition, fitness, and brain structure and function in older adults with mild cognitive impairment.

Brain Connections, Self-Care, and Blood Pressure in African Americans with Memory Problems

Purpose:To evaluate a dietary and mindfulness intervention to decrease blood pressure and improve brain function in black and African-American older adults with high blood pressure and early Alzheimer's disease or a related dementia.

Curcumin and Yoga Therapy for Mild Cognitive Impairment

Purpose: To test the clinical benefits of curcumin, a compound isolated from turmeric root, and a yoga-based physical exercise program in individuals with early memory problems.

Exercise and Vascular Risk Reduction for Alzheimer's

Purpose: To test the effects of exercise and vascular risk reduction on cognitive performance in older adults at high risk for Alzheimer's.

Exercise for Brain Health

Purpose: To compare the effects of moderate- and low-intensity exercise on brain function, cognition, and physical function in cognitively healthy, physically inactive older adults.

Exercise in Adults with Mild Memory Problems (EXERT)

Purpose: To evaluate the effects of physical exercise on cognition, functional status, brain atrophy, blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.

Exercise to Improve Cognitive Function in Veterans with MCI

Purpose: To assess the feasibility of a home-based exercise intervention to improve memory in veterans with mild cognitive impairment.

Independent Walking in Older Adults for Brain Health

Purpose: To test the use of mobile health devices in helping older adults independently walk to improve cognitive health.

Investigating Gains in Neurocognition in an Intervention Trial of Exercise (IGNITE)

Purpose: To examine whether a 12-month exercise intervention improves brain health in cognitively normal older adults.

Lifestyle Activities for Brain Health

Purpose: To evaluate the effect of exercise and healthy living education on brain health, cognition, and physical function in older adults with cognitive concerns.

Physical Activity and Alzheimer's Disease (PAAD-2)

Purpose: To assess the effects of exercise on middle-aged cognitively normal adults who have a family history of Alzheimer's disease.

Physical Activity with a Body-Worn Sensor

Purpose: To assess the effect on cognition of increasing physical activity using a body-worn sensor in older adults.

Precision Rehabilitation to Counteract Age-Related Cognitive Decline

Purpose: To examine how different types of training activities affect older adults' cognitive function, brain structure, biomarkers of brain health and cognition, and physical function.

Preventing Loss of Independence Through Exercise in Mild Cognitive Impairment (PLIE)

Purpose: To test an exercise program in older adults with mild cognitive impairment.

U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk (U.S. POINTER)

Purpose: To test the effects of lifestyle changes on memory loss and thinking in older Americans who are at risk for memory loss.

Water-based Activity to Enhance Recall in Veterans (WATER-VET)

Purpose: To evaluate the feasibility of a water-based exercise program with cognitive training to improve memory in veterans with mild cognitive impairment.