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Find Alzheimer’s Disease and Related Clinical Trials

Search for clinical trials and studies related to Alzheimer's, other dementias, mild cognitive impairment, and caregiving.

Clinical Trials Search Results

Results found: 24

Alzheimer's Caregiver Coping: Mental and Physical Health

Purpose: To compare two intervention strategies for reducing emotional and cardiovascular disease risk in Alzheimer's caregivers.

This Study Will Compare Two Intervention Strategies For Reducing Emotional And Cardiovascular Disease Risk In Alzheimer's Caregivers: Behavioral Activation Therapy And Support And Information.

Alzheimer's Disease, Caregiving, and Social Networks

Purpose: To study how multiple family members provide care for a person with Alzheimer's disease.

Most Studies On Alzheimer's Disease (AD) Caregiving Focus On The Primary Caregiver. More Research Is Needed On How The Disease Affects The Broader Family Network. In This Study, Researchers Will Examine Caregiving In A Family Social Network To consider How All Family Caregivers Adapt To Their Roles. At Least One Caregiver And One Family Member Who Provides Care Indirectly (e.g., Supports The Caregiver) Will Be Surveyed. Researchers Will Also Compare levels Of Perceived Family Health History Risk.

Alzheimer's Prevention Registry

Purpose: To enroll individuals who are interested in learning about and possibly participating in Alzheimer's prevention clinical studies and trials in a national registry.

The Alzheimer's Prevention Registry Is A National Registry Of Individuals Age 18 And Older Who Are Interested In Learning About And Possibly Participating In Alzheimer's Prevention Clinical Studies And Trials. The Registry Will Collect Contact And Demographic Information, Provide Information About The Latest News And Advances In Alzheimer's Prevention Research, And Inform Enrollees About Research Studies In Their Community.

Behavioral and Environmental Sensing and Intervention (BESI)

Purpose: To develop and assess a tool enabling caregivers to recognize dementia-related agitation and intervene before it escalates.

The Goal Of This Study Is To Develop and Evaluate A Tool To Help Caregivers Recognize Dementia-related Agitation And Intervene Before The Distress Escalates. The Tool Is Designed To Help Reduce Caregiver Burden And Extend Aging-in-place For People With Dementia.

Brain Care for Veterans with Alzheimer's or Traumatic Brain Injury (ABC ANSWERS)

Purpose: To test an intervention for caregivers of veterans with Alzheimer's disease or traumatic brain injury.

Most people With Alzheimer's Disease Or Traumatic Brain Injury receive Significant Amounts Of Care From family Members Or Friends. This Study Will Test An Intervention That Is Designed To Improve The Informal Care Of Veterans With Alzheimer's Disease Or Traumatic Brain Injury And To Reduce The Burden On Their caregivers.

Brain Health Registry

Purpose: To enroll people interested in participating in brain health research in an ongoing online registry.

The Purpose Of The Online Brain Health Registry Is To Recruit And Observe People Who Are Interested In Promoting Healthy Brain Function Through The Prevention Of Brain Diseases, Disorders, And Injuries In Adults. Participation Involves Answering Questions About Your Health, Lifestyle, And Medical History And Taking Online Brain Tests. Researchers Hope To Build A Large Pool Of Potential Participants For Clinical Trials, Reducing The Time And Cost Of Research.

Care Partners Program for Alzheimer's Disease

Purpose: To develop and test a tablet-based caregiving program for family caregivers of people with Alzheimer's disease.

In This Study, Researchers Will Develop And Test A Tailored, Tablet-based Program For Family Caregivers Of People With Alzheimer's Disease. The Program Will Combine An Evidenced-based Caregiver Intervention And Cognitive Training For The Person With Alzheimer's.

Caregiver Outcomes of Alzheimer's Disease Screening

Purpose: To measure the risks and benefits of early screening for Alzheimer's disease in terms of its effects on family caregivers.

This Randomized Controlled Trial Will Measure The Risks And Benefits Of Early Screening For Alzheimer's Disease In Terms Of Its Effects On Family Caregivers. Early Diagnosis Through Screening May Enhance The Family Member's Transition To Caregiving And Reduce Caregiver Burden By Providing An Opportunity For The Family Member To Learn About The Syndrome, Receive Interventions, And Prepare For The New Caregiving Role.

Cross-Cultural Comparison of Alzheimer's Symptoms and Caregiving

Purpose: To compare Alzheimer's disease caregiving in the United States and Mexico.

This Interview-based Study Compares Alzheimer's Disease caregiving In The United States And Mexico. The Goal Is To Identify Cross-cultural Differences In Order To Identify Strategies That May reduce The Burden Of The Disease On Family Caregivers. 

Early-Onset Alzheimer's Disease Genomic Study

Purpose: To better understand how changes in the body are related to the development of early-onset Alzheimer's disease.

This Study Will Collect Samples From People With Early-onset Alzheimer's Disease And Their Immediate Family Members to Better Understand How Changes In The Body Are Related To Development Of The Disease.

Early-Stage Partners in Care for Memory Loss and Dementia (EPIC)

Purpose: To test training for care partners and people with early-stage memory loss or dementia to reduce stress and increase well-being and quality of life.

This Study Will Test An Education And Skills-based Training Program For People With Early-stage Memory Loss Or Dementia And Their Care Partners. The Training Is Designed To Reduce Stress And Distress, And Increase Well-being And Quality Of Life.

Family Telemental Health Intervention for Veterans with Dementia

Purpose: To develop and test a telehealth intervention to address interpersonal difficulties between caregivers and persons with dementia in families with veterans.

This Research Project Will Develop A Telehealth Intervention To Address Interpersonal Difficulties Between Caregivers And Persons With Dementia In Families With Veterans.

Home Visits for Progressive Supranuclear Palsy and Related Disorders (CarePSP)

Purpose: To test a home visit program designed to assess the needs of people with progressive supranuclear palsy (PSP) or related disorders and to connect them with services.

This Study Will Test A Home Visit Program Designed To Assess The Needs Of People With Progressive Supranuclear Palsy Or Related Disorders And to Connect Them With Services.

Improvisational Movement for People with Memory Loss and Their Caregivers (IMOVE)

Purpose: To determine the effects of dance movement and social engagement on quality of life in older adults with mild cognitive impairment or early Alzheimer's disease.

This Study Will Test Dance And Social Engagement As A Method To Decrease Behavioral Symptoms And Improve Quality Of Life In Older Adults With Mild Cognitive Impairment (MCI) Or Early Alzheimer's Disease.

Interventions for Circadian Rhythm Disorders in Dementia (Healthy Patterns Sleep Study)

Purpose: To evaluate a program of activities to improve symptoms of disturbed sleep-wake cycles in people with dementia who live at home.

This Phase III clinical Trial Will Evaluate A 1-month, 8-session Program For Caregivers That Provides Instruction In Activities To Improve Symptoms Of Disturbed Sleep-wake Cycles In  People with Dementia Who Live At Home.

Optimizing Dementia Care for Veterans and Their Caregivers

Purpose: To examine the effectiveness of an established counseling approach and a variation of it for veterans with dementia and their family caregivers who have high levels of stress. 

This Study Will Compare Care Consultation With A More Intensive Variation Of It For Veterans With Dementia And Their Family Caregivers Who Are Experiencing High Levels Of Stress. Researchers Will Compare The Impact Of The Intervention On Quality Of Life, Care Burden, And Other Factors. Care Consultation Is An Established, Telephone-based Intervention That Uses Coaching And Emotional Support To Help Family Caregivers And Individuals With Dementia Through Education, Resource Referral, Psychosocial Support, And Encouragement To Use Services.

Palliative Care for Parkinson's and Related Disorders

Purpose: To compare usual care to palliative care for adults with Parkinson's disease and related disorders.

For Individuals With Chronic, Progressive Illnesses, Palliative Care Addresses Potential Causes Of Suffering, Including Physical And Psychiatric Symptoms, Psychosocial Issues, And Spiritual Needs. This Study Will Compare Usual Care In The Community To Care Augmented By Palliative Training And Telemedicine Support For People With Parkinson's Disease And Related Disorders, Including Progressive Supranuclear Palsy, Corticobasal Degeneration, Multiple System Atrophy, And Lewy Body Dementia.

Performing Arts for Alzheimer's Dementia Caregivers

Purpose: To examine whether a performing arts class will improve the well-being of primary unpaid caregivers of people with Alzheimer's dementia.

This Study Will Examine The Effect Of A Performing Arts Class On Improving The Well-being Of Caregivers Of Older Adults With Alzheimer's Dementia.

Practice of Acceptance, Awareness, and Compassion in Caregiving (PAACC)

Purpose: To evaluate a mindfulness-based intervention for caregivers of people with dementia.

This Study will Evaluate The Effectiveness Of A Mindfulness-based Caregiver Intervention That Is Designed To Improve The Caregiver's Burden And The Care Recipient's Quality Of Life. Care Recipients Have Alzheimer's Disease Or A Related Dementia.

Residential Care Transition for Family Caregivers

Purpose: To evaluate a program for decreasing caregiver distress and strain after transitioning a cognitively impaired relative to long-term care.

This Study Will Explore The Effect Of Consultation Sessions On Reducing Distress And Strain In Family Caregivers Who Have Transitioned A Cognitively Impaired Relative To Long-term Care.

SPIRIT for End-of-Life Decision Making in Mild Alzheimer's

Purpose: To adapt and test an advance care planning intervention, Sharing Patient's Illness Representations to Increase Trust (SPIRIT), in older adults with mild Alzheimer's disease and their surrogates to promote end-of-life care discussions.

This Study Will Test An Advance Care Planning Intervention Called Sharing Patient's Illness Representations To Increase Trust, Or SPIRIT, For People With Mild Alzheimer's Disease And Their Surrogates To Promote Early Discussions About End-of-life Care.

Tele-Savvy Education Program for Dementia Caregivers

Purpose: To test an Internet-based education program for dementia caregivers.

This Study Is Testing An Internet-based Education Program For Caregivers Of People With Alzheimer's Or Another Dementia.

Training to Reduce Care-Resistant Behaviors in Alzheimer's and TBI (NeuroNS-Care)

Purpose: To test a distance-learning training program for family caregivers of people with Alzheimer's or TBI in reducing care-resistant behaviors.

This Study Will Test The Effectiveness Of An Internet-based Distance-learning Program In Reducing Care-resistant Behaviors, Including Agitation, Aggression, And Irritability, In People With Alzheimer's Disease Or Traumatic Brain Injury (TBI).

VA Cultivating Access to Resources, Education, and Skills for Dementia Caregivers (VA CARES)

Purpose: To study the effects of an education and skill-building intervention on family caregivers of veterans with dementia.

The Purpose Of This Study Is To Study The Effects Of An Education And Skill-building Intervention On Family Caregivers Of Veterans With Dementia.