Find Alzheimer’s Disease and Related Clinical Trials
Search for clinical trials and studies related to Alzheimer's, other dementias, mild cognitive impairment, and caregiving.
Results found: 30
Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Purpose: To learn about thinking and behavior in families in which one or more relatives has a genetic mutation associated with frontotemporal dementia.
Purpose: To document the clinical features and biological markers of people with synucleinopathies (Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy).
Purpose: To investigate pupillary light response as a potential identifier of progressive supranuclear palsy (PSP).
Purpose: To study changes in cognitive function in adults with early-stage behavioral variant frontotemporal dementia.
Purpose: To identify and distinguish two different types of progressive apraxia of speech (PAOS) through clinical imaging and testing in adults with PAOS.
Purpose: To evaluate a new radioactive compound used in positron emission tomography scans in identifying tau tangles.
Purpose: To test how different types of meals affect Alzheimer's biomarkers in healthy older adults with and without the APOE E4 genotype.
Purpose: To examine cognitive and neural biomarkers in adults who are overweight or obese and younger than 50.
Purpose: To examine the impact on older adults of learning the results of amyloid brain imaging.
Purpose: To identify reliable methods for tracking corticobasal degeneration and progressive supranuclear palsy.
Purpose: To establish a bank of blood, cerebrospinal fluid, imaging, and clinical data to be used in Alzheimer's disease research.
Purpose: To validate several novel cognitive tasks and correlate them with Alzheimer's disease biomarkers in people who are cogntitively normal or have mild cognitive impairment.
Purpose: To evaluate a new radioactive compound used in positron emission tomography scans to identify tau tangles.
Purpose: To use magnetic resonance imaging to investigate brain function and connections in healthy adults.
Purpose: To determine if the presence of beta-amyloid plaques in the brains of non-demented patients before hip or knee replacement surgery predicts cognitive decline after surgery.
Purpose: To evaluate the effects of surgical anesthesia on cognition and certain Alzheimer's disease biomarkers in older adults who undergo surgery.
Purpose: To study how women undergoing breast cancer treatment may develop brain changes related to the development of mild cognitive impairment.
Purpose: To test the safety and effectiveness of the drug riluzole for treating mild Alzheimer's disease.
Purpose: To determine if the drug memantine can improve learning and memory in adolescents and young adults with Down syndrome.
Purpose: To use positron emission tomography imaging with a new radioactive tracer 18F-MK-6240 to understand the cognitive and behavioral outcomes of tau deposition in specific brain regions in cognitively normal and mildly cognitively impaired older adults.
Purpose: To test the effect of the investigational drug CT1812 on brain synaptic density in adults with mild to moderate Alzheimer's disease.
Purpose: To look at disease progression in adults with early-onset Alzheimer's disease.
Purpose:To better understand the relationship between APOE genotype and metabolism by testing metabolic rate at rest and during a cognitive challenge in healthy adults.
Purpose: To develop better measures for diagnosis and treatment of Lewy body dementia by studying older adults with the condition.
Purpose: To determine the relationships among clinical, cognitive, imaging, genetic, and biomarker characteristics of the entire spectrum of Alzheimer's disease.
Purpose: To study brain changes in veterans with traumatic brain injury or post traumatic stress disorder, with and without mild cognitive impairment.
Purpose: To study memory and aging in healthy older adults.
Purpose: To examine the sensitivity of functional MRI to detect brain changes in healthy older adults at genetic risk for Alzheimer's disease who take donepezil (Aricept).
Purpose: To prescreen older adults with early Alzheimer’s disease who may be eligible for therapeutic trials requiring tau imaging.