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Find Alzheimer’s Disease and Related Clinical Trials

Search for clinical trials and studies related to Alzheimer's, other dementias, mild cognitive impairment, and caregiving.

Clinical Trials Search Results

Results found: 22

Apathy in Dementia Methylphenidate Trial 2 (ADMET 2)

Purpose: To test methylphenidate (Ritalin®) as a treatment for clinically significant apathy in people with Alzheimer's disease.

Behavioral and Environmental Sensing and Intervention (BESI)

Purpose: To develop and assess a tool enabling caregivers to recognize dementia-related agitation and intervene before it escalates.

Brexpiprazole for Agitation in Alzheimer's

Purpose: To compare the efficacy of two doses of brexpiprazole (Rexulti) in older adults with agitation associated with Alzheimer's disease.

Cognitive Behavioral Therapy for African Americans with MCI

Purpose: To test the effects of a cognitive-behavioral therapy program on cognitive performance and stress levels in African-American adults with mild cognitive impairment.

D-CARE: The Dementia Care Study

Purpose: To compare the effectiveness of two evidence-based models of dementia care.

Early-Stage Partners in Care for Memory Loss and Dementia (EPIC)

Purpose: To test training for care partners and people with early-stage memory loss or dementia to reduce stress and increase well-being and quality of life.

Escitalopram for Agitation in Alzheimer's Disease

Purpose: To evaluate the safety and efficacy of escitalopram (Lexapro) to treat agitation in Alzheimer's disease.

Family Telemental Health Intervention for Veterans with Dementia

Purpose: To develop and test a telehealth intervention to address interpersonal difficulties between caregivers and persons with dementia in families with veterans.

Improvisational Movement for People with Memory Loss and Their Caregivers (IMOVE)

Purpose: To determine the effects of dance movement and social engagement on quality of life in older adults with mild cognitive impairment or early Alzheimer's disease.

Indiana Palliative Excellence in Alzheimer's Care Efforts (IN-PEACE)

Purpose: To test the effect of a telephone-based intervention on reducing the burdens of dementia-associated symptoms and behaviors.

Interventions for Circadian Rhythm Disorders in Dementia (Healthy Patterns Sleep Study)

Purpose: To evaluate a program of activities to improve symptoms of disturbed sleep-wake cycles in people with dementia who live at home.

Light for Metabolic Syndrome and Alzheimer's

Purpose: To test the effects of a tailored lighting system on sleep, mood, inflammation, and glucose tolerance in older adults with Alzheimer's disease or a related dementia and type 2 diabetes.

Mind-Body Skills and Physical Activity for MCI and Chronic Pain

Purpose: To adapt and examine a mind-body program, called Active Brains, to meet the needs of older adults with chronic pain and mild cognitive impairment.

Nighttime Agitation and Restless Legs Syndrome in Nursing Home Residents with Alzheimer's

Purpose:To test whether Horizant, a drug approved for treating restless legs syndrome (RLS), could reduce nighttime agitation and improve sleep in nursing home residents with Alzheimer's and RLS.

Optimizing Dementia Care for Veterans and Their Caregivers

Purpose: To examine the effectiveness of an established counseling approach and a variation of it for veterans with dementia and their family caregivers who have high levels of stress. 

Self-Management of Chronic Pain and Negative Emotions

Purpose: To examine the effects of an intervention to reduce negative emotions and pain in older adults who are cognitively normal or have mild cognitive impairment.

Targeting Verbal Short-Term Memory in Conjunction with tDCS in Neurodegenerative Disorders

Purpose: To investigate the effects of transcranial direct current stimulation during short-term memory therapy in people with primary progressive aphasia and related neurodegenerative conditions.

Tele-Savvy Education Program for Dementia Caregivers

Purpose: To test an Internet-based education program for dementia caregivers.

Training for Optimal Routines in Mild Cognitive Impairment

Purpose: To test the effects of a behavioral intervention known as strategy training on the progression of disability in older adults with mild cognitive impairment.

Training to Reduce Care-Resistant Behaviors in Alzheimer's and TBI (NeuroNS-Care)

Purpose: To test a distance-learning training program for family caregivers of people with Alzheimer's or TBI in reducing care-resistant behaviors.

Treatment of Psychosis and Agitation in Alzheimer's Disease

Purpose: To test lithium as a treatment for psychosis and agitation in older adults with Alzheimer's disease.

Weighted Blankets to Decrease Agitation in Dementia

Purpose: To evaluate whether weighted blankets can reduce agitation in hospitalized patients with dementia.