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Find Alzheimer’s Disease and Related Clinical Trials

Search for clinical trials and studies related to Alzheimer's, other dementias, mild cognitive impairment, and caregiving.

Clinical Trials Search Results

Results found: 30

Adult Day Plus Program for Family Caregivers

Purpose: To evaluate the effectiveness of an adult day services program to improve the well-being of caregivers of older adults with Alzheimer's disease.

Behavioral and Environmental Sensing and Intervention (BESI)

Purpose: To develop and assess a tool enabling caregivers to recognize dementia-related agitation and intervene before it escalates.

Brexpiprazole for Agitation in Alzheimer's

Purpose: To compare the efficacy of two doses of brexpiprazole (Rexulti) in older adults with agitation associated with Alzheimer's disease.

Caring Response: A Mobile Training App for Family Caregivers

Purpose: To determine if the mobile training app, Caring Response, can improve coping skills and quality of life for family caregivers of someone with Alzheimers disease.

D-CARE: The Dementia Care Study

Purpose: To compare the effectiveness of two evidence-based models of dementia care.

Early-Stage Partners in Care for Memory Loss and Dementia (EPIC)

Purpose: To test training for care partners and people with early-stage memory loss or dementia to reduce stress and increase well-being and quality of life.

Escitalopram for Agitation in Alzheimer's Disease

Purpose: To evaluate the safety and efficacy of escitalopram (Lexapro) to treat agitation in Alzheimer's disease.

Family Telemental Health Intervention for Veterans with Dementia

Purpose: To develop and test a telehealth intervention to address interpersonal difficulties between caregivers and persons with dementia in families with veterans.

Improvisational Movement for People with Memory Loss and Their Caregivers (IMOVE)

Purpose: To determine the effects of dance movement and social engagement on quality of life in older adults with mild cognitive impairment or early Alzheimer's disease.

Indiana Palliative Excellence in Alzheimer's Care Efforts (IN-PEACE)

Purpose: To test the effect of a telephone-based intervention on reducing the burdens of dementia-associated symptoms and behaviors.

Innovations in Dementia Empowerment and Action

Purpose: To test a tailored behavioral intervention for LGBT individuals with Alzheimer's disease or a related dementia and their caregivers.

Insomnia Therapy for People Living With Dementia and Their Caregivers

Purpose: To test cognitive behavioral therapy for insomnia to improve the sleep of community-dwelling persons living with dementia and their caregivers.

Interventions for Circadian Rhythm Disorders in Dementia (Healthy Patterns Sleep Study)

Purpose: To evaluate a program of activities to improve symptoms of disturbed sleep-wake cycles in people with dementia who live at home.

Interventions for People with Alzheimer's Disease and Dysphagia (Swallowing Problems)

Purpose: To develop effective interventions that improve swallowing for people with Alzheimer's Disease at risk for pneumonia.

Light for Metabolic Syndrome and Alzheimer's

Purpose: To test the effects of a tailored lighting system on sleep, mood, inflammation, and glucose tolerance in older adults with Alzheimer's disease or a related dementia and type 2 diabetes.

Light, Metabolic Syndrome, and Alzheimer's Disease

Purpose:: To test the long-term effect of a light treatment on cognition, sleep, and metabolism in people with MCI, mild Alzheimer's disease, or a related dementia.

Mind-Body Skills and Physical Activity for MCI and Chronic Pain

Purpose: To adapt and examine a mind-body program, called Active Brains, to meet the needs of older adults with chronic pain and mild cognitive impairment.

Mobile App to Monitor Dementia-Related Agitation

Purpose: To test a mobile application designed to monitor and support individuals with dementia-related agitation.

Nighttime Agitation and Restless Legs Syndrome in Nursing Home Residents with Alzheimer's

Purpose:To test whether Horizant, a drug approved for treating restless legs syndrome (RLS), could reduce nighttime agitation and improve sleep in nursing home residents with Alzheimer's and RLS.

Oral Hygiene in Assisted Living

Purpose: To evaluate a program that provides daily mouth care for assisted living residents with dementia.

Palliative Care for Cognitively Impaired People and Their Families

Purpose: To evaluate the benefits of an early palliative-care intervention for people with cognitive impairment and their family caregivers.

Pimavanserin for Psychological Symptoms of Dementia

Purpose: To determine whether treatment with the drug pimavanserin decreases the psychological symptoms of dementia in older adults.

Problem Adaptation Therapy for Mild Cognitive Impairment and Depression

Purpose: To compare Problem Adaptation Therapy to Supportive Therapy for improving cognitive, affective and functioning outcomes in people with mild cognitive impairment.

Sleep Intervention for People with Alzheimer's Disease and their Caregivers

Purpose: To develop a sleep intervention program for people with Alzheimer's disease and their caregivers, who both experience sleep difficulties.

SmartPrompt Electronic Reminder Aid to Improve Everyday Function in People With Dementia

Purpose: To evaluate the use of SmartPrompt, a smartphone-based electronic reminder aid that is designed to help older adults with dementia perform daily tasks.

Targeting Verbal Short-Term Memory in Conjunction with tDCS in Neurodegenerative Disorders

Purpose: To investigate the effects of transcranial direct current stimulation during short-term memory therapy in people with primary progressive aphasia and related neurodegenerative conditions.

Telephone Therapy for Alzheimer's Caregivers

Purpose: To test a telephone-based behavioral intervention designed to reduce anxiety and associated psychological distress in dementia caregivers.

The STELLA Collaborative: Using Technology to Advance Alzheimer's Disease and Related Dementias Family Education and Support

Purpose: To study the use of a videoconference-based system known as Support via Technology: Living and Learning with Advancing Alzheimer's Disease and Related Dementias to provide education and support to family caregivers, as well as the person with dementia.

Training for Optimal Routines in Mild Cognitive Impairment

Purpose: To test the effects of a behavioral intervention known as strategy training on the progression of disability in older adults with mild cognitive impairment.

Weighted Blankets to Decrease Agitation in Dementia

Purpose: To evaluate whether weighted blankets can reduce agitation in hospitalized patients with dementia.