Skip to main content
U.S. flag

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock (  ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Find more clinical trials

Preventing Loss of Independence Through Exercise in Mild Cognitive Impairment (PLIE)

Start: August 30, 2018
End: October 2020
Enrollment: 40

What Is This Study About?

This randomized, controlled trial will test the an exercise program in older adults with mild cognitive impairment (MCI) who live in the community.

Do I Qualify To Participate in This Study?

Minimum Age: 60 Years

Maximum Age: N/A

Must have:

  • Mild cognitive impairment 
  • English fluency
  • Able to take two steps without a cane or walker
  • Living in the community in a private home or apartment

Must NOT have:

  • Behavioral or physical issues that would be disruptive or dangerous (e.g., active psychosis, drug abuse, severe behavioral issues)
  • Physical or mental health condition that would make participation difficult (e.g., active psychosis, limited life expectancy)
  • Contraindications to magnetic resonance imaging, including severe claustrophobia or metal objects in the body such as pacemakers, implanted stimulators, or pumps
  • Started dementia medication (cholinesterase inhibitor or memantine) within the past 3 months
  • Planning to start or change any psychotropic medication during the study period
  • Current participation in another research study

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: University of California, San Francisco

Collaborator Sponsor

  • United States Department of Defense

Source: ClinicalTrials.gov ID: NCT03526146

alzheimers.gov

An official website of the U.S. government, managed by the National Institute on Aging at the National Institutes of Health