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Multicultural Healthy Diet to Reduce Cognitive Decline

Recruiting

This 18-month trial is designed to investigate whether the Multicultural Healthy Diet, an anti-inflammatory diet tailored to a multicultural population, can improve cognitive functioning in urban-dwelling adults.

Minimum Age Maximum Age Gender Healthy Volunteers
40 Years 65 Years All Yes
October 2, 2018
September 14, 2022
326

  • Resident of Co-op City, Bronx, NY
  • Willingness to accept assignment to intervention or comparison diet group
  • Willingness to participate in a study in which weight loss is not a primary goal
  • Sub-optimal diet

  • Cognitively impaired
  • History of traumatic brain injury
  • Psychiatric illness
  • History of diabetes treated with a medication that may cause hypoglycemia
  • Kidney or liver disease
  • Uncontrolled high blood pressure (greater than 140/90 mmHg)
  • History of heart disease
  • Severe chronic illness
  • Low literacy
  • History of alcohol or drug dependence
  • Blood disease or malignancy not in remission for more than 5 years
  • Visual, hearing, or motor impairment that would interfere with cognitive testing
  • Chronic kidney disease

The Multicultural Healthy Diet emphasizes plant-based foods and limited animal and high-saturated fat foods. Participants will be randomly assigned to either the study diet or to their usual diet plus sessions that focus on self-care, such as dealing with aches and pains of aging and obtaining a healthcare proxy. Researchers will measure changes in cognitive function through assessments, as well as changes in biological markers of oxidative stress and inflammation.

Name City State Zip Status Primary Contact
Albert Einstein College of Medicine
Bronx New York 10461 Recruiting Vanessa Claris, B.S.
718-430-3823
vanessa.claris@einstein.yu.edu

Albert Einstein College of Medicine, Inc.

  • Penn State University
  • University of Pennsylvania
  • University of Minnesota - Clinical and Translational Science Institute
  • National Institute on Aging (NIA)

Name Role Affiliation
Yasmin Mossavar-Rahmani, Ph.D, RD Principal Investigator Albert Einstein College of Medicine, Inc.

Name Phone Email
Yasmin Mossavar-Rahmani, Ph.D., RD 718-430-2136 yasmin.mossavar-rahmani@einstein.yu.edu
Mindy Katz 718-430-3885 mindy.katz@einstein.yu.edu

NCT03240406

Multicultural Healthy Diet to Reduce Cognitive Decline & Alzheimer's Disease Risk