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Light for Metabolic Syndrome and Alzheimer's


This study will test the effects of a tailored lighting intervention on mood, behavior, and factors associated with metabolic syndrome in people living in a controlled environment, such as a nursing home or assisted living facility, with mild to moderate Alzheimer's disease or a related dementia and type 2 diabetes.

Minimum Age Maximum Age Gender Healthy Volunteers
55 Years N/A All No
November 1, 2018
October 31, 2023

  • Diagnosis of mild to moderate Alzheimer's disease or related dementia
  • Type 2 diabetes
  • Sleep disturbance as determined by a score of 5 on the Pittsburgh Sleep Quality Index

  • Insulin-dependent diabetes
  • Urinary incontinence
  • Cataracts that obstruct vision
  • Macular degeneration
  • Blindness
  • Severe sleep apnea
  • Restless leg syndrome

Metabolic syndrome is the name for a group of risk factors, such as high fasting blood sugar, that raise a person's risk for heart disease and other health problems, such as diabetes and stroke. The lighting intervention in this study is designed to increase circadian entrainment, which is the alignment of circadian rhythm to external time cues, such as the light-dark cycle. Participants will be randomly assigned to 8 weeks of the tailored lighting intervention or to a control light. After an 8-week period, participants will rotate groups. Researchers will measure whether the intervention improves sleep, depression, inflammation, and glucose tolerance. 

Name City State Zip Status Primary Contact
Rensselaer Polytechnic Institute
Troy New York 12180 Recruiting Barbara Plitnick, RN

Rensselaer Polytechnic Institute

  • Icahn School of Medicine at Mount Sinai

Name Role Affiliation
Mariana Figueiro, PhD Principal Investigator Rensselaer Polytechnic Institute

Name Phone Email
Mariana Figueiro, PhD 518-687-7142


Light, Metabolic Syndrome and Alzheimer's Disease: A Non-Pharmocological Approach