Indiana University Dementia Screening Trial
Active, not recruiting
This study will assess the harms and benefits of screening for dementia, compared to no screening for dementia, among 4,000 older adults cared for in primary care practices at Wishard Health Services and Indiana University in Indianapolis.
|Minimum Age||Maximum Age||Gender||Healthy Volunteers|
- At least one office visit to a primary care physician within the previous year
- No previous diagnosis of dementia or memory problems
- Ability to communicate in English
- Permanent resident of a nursing facility
- Serious mental illness such as bipolar disorder or schizophrenia
- Pre-existing diagnosis of dementia or cognitive impairment
This study will evaluate whether the benefits outweigh the harms of routine screening for dementia among older adults in primary care, when the screening program is coupled with practices ready to provide care for those who screen positive. Participants will be randomized to receive either dementia screening or the usual standard of care with no screening. As appropriate, participants will be referred to the Collaborative Dementia Care Program at Indiana University for a subsequent diagnostic assessment, counseling, and management. Researchers will assess the impact of screening on participants' health-related quality of life and mood and anxiety symptoms. They will also study the cost-effectiveness of screening.
IU Health-Primary Care Clinics
Wishard Health Services-Primary Care Clinics
IU Health Arnett Primary Care Clinics
Regenstrief Institute, Indiana University Center for Aging Research
- National Institutes of Health
- National Institute on Aging
|Malaz Boustani, MD, MPH||Principal Investigator||Regenstrief Institute, IU Center for Aging Research|
Indiana University Dementia Screening Trial: The IU CHOICE Study
- Boustani M, Perkins AJ, Monahan P, Fox C, Watson L, Hopkins J, Fultz B, Hui S, Unverzagt FW, Callahan CM, Hendrie HC. Measuring primary care patients' attitudes about dementia screening. Int J Geriatr Psychiatry. 2008 Aug;23(8):812-20.
- Boustani M, Peterson B, Hanson L, Harris R, Lohr KN; U.S. Preventive Services Task Force. Screening for dementia in primary care: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med. 2003 Jun 3;138(11):927-37. Review.
- Boustani MA, Justiss MD, Frame A, Austrom MG, Perkins AJ, Cai X, Sachs GA, Torke AM, Monahan P, Hendrie HC. Caregiver and noncaregiver attitudes toward dementia screening. J Am Geriatr Soc. 2011 Apr;59(4):681-6. doi: 10.1111/j.1532-5415.2011.03327.x. Epub 2011 Mar 25.
- Fowler NR, Boustani MA, Frame A, Per