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Find more clinical trials

Genetic Characterization of Movement Disorders and Dementias

Start: February 12, 2003
End: December 2059
Enrollment: 12000

What Is This Study About?

In this observational study, researchers will examine the genes of families with a history of movement disorders (such as Parkinson's disease) and dementias (such as Alzheimer's disease) to try to find a genetic cause of these disorders. Participants include individuals with a clinical diagnosis of a movement disorder or dementia, their affected and unaffected family members, and unrelated, healthy individuals (to provide control samples). This study usually requires one visit to the NIH Clinical Center where participants will give a blood sample and/or a saliva sample.

Do I Qualify To Participate in This Study?

Minimum Age: 18 Years

Maximum Age: 100

Must have:

  • Diagnosis of a movement disorder or dementia accompanied by sufficient clinical and/or laboratory evidence
  • Clinical confirmation of a movement disorder or dementia by the investigator and his associates, either by physical examination and/or review of medical records
  • Family member of a person diagnosed with a movement disorder or dementia
  • Have no known movement disorder or dementia, or family member with a movement disorder or dementia
  • Able to provide consent or, in the case of minors and cognitively impaired individuals, have a legally authorized representative to provide consent
  • Able to understand and participate in study procedures or have a legally authorized representative that can consent on participant's behalf

Must NOT have:

  • Any movement disorder or dementia caused by a specific environmental exposure, birth injury, metabolic disorder, or brain infection such as encephalitis
  • Clinically significant anemia that would make drawing blood unsafe, and participant is unwilling to provide saliva sample
  • Clinically significant bleeding that would make drawing blood unsafe, and participant is unwilling to provide saliva sample
  • Any medical condition that would make drawing blood unsafe or undesirable (for example, a serious medical illness such as unstable heart disease or unstable chronic obstructive pulmonary disease), and participant is unwilling to provide saliva sample

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Study Contact
Bryan J Traynor, M.D.

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Maryland
National Institute of Aging, Clinical Research Unit
Baltimore, MD 21224
Recruiting
NIA Studies Recruitment

Who Sponsors This Study?

Lead: National Institute on Aging (NIA)

Source: ClinicalTrials.gov ID: NCT02014246

alzheimers.gov

An official website of the U.S. government, managed by the National Institute on Aging at the National Institutes of Health