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Cognitive Rehabilitation for Older Veterans with MCI

Recruiting

This study will evaluate the effectiveness of a cognitive rehabilitation group treatment for veterans with mild cognitive impairment (MCI).

Minimum Age Maximum Age Gender Healthy Volunteers
55 Years N/A All No
July 11, 2018
December 30, 2022
216

  • Enrolled at a participating Veterans Affairs site
  • Living independently
  • Meets criteria for MCI:
    • Concern about a decline in cognitive functioning expressed by a physician, informant, participant, or nurse
    • Cognitive impairment in one or more domains (executive function, memory, attention, language, or visuospatial abilities)
    • Normal or minimal impairment in functional activities
  • Does not meet criteria for dementia

  • Current substance use disorder
  • History of schizophrenia, schizoaffective disorder, or other primary psychotic disorder
  • History of significant brain injury
  • Auditory or visual impairments that would prevent ability to participate in the group session

Participants will be randomized to receive Motivationally Enhanced Compensatory Cognitive Training (ME-CCT), focusing on cognitive strategies, lifestyle strategies, and motivational enhancement, or training in short- and long-term goal setting. Both groups will be provided eight 2-hour therapist-led sessions. Researchers will evaluate whether ME-CCT improves cognitive performance, functional capacity, and subjective complaints and concerns about cognition. They also will measure the extent to which ME-CCT helps participants change eating, exercise, and other behaviors associated with reduced risk for MCI.

Name City State Zip Status Primary Contact
VA San Diego Healthcare System, San Diego, CA
San Diego California 92161 Recruiting Amber V Keller, BA
858-642-3878
amber.keller@va.gov
VA Portland Health Care System, Portland, OR
Portland Oregon 97239 Recruiting Marilyn Huckans, PhD
503-220-8262
marilyn.huckans@va.gov

VA Office of Research and Development

  • Portland VA Medical Center

Name Role Affiliation
Elizabeth W. Twamley, PhD Principal Investigator VA San Diego Healthcare System, San Diego, CA

Name Phone Email
Elizabeth W. Twamley, PhD 858-552-8585 Elizabeth.Twamley@va.gov
Amber Keller, BA 858-642-3878 amber.keller@va.gov

NCT03225482

Cognitive Rehabilitation for Older Veterans With Mild Cognitive Impairment