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Coaching for Cognition in Alzheimer's and MCI (COCOA)


The COCOA study will test the effects of 2 years of coaching in adults with mild cognitive impairment (MCI) and Alzheimer's disease. Researchers believe that providing coaching, in addition to routine care, may improve memory, cognitive function, and quality of life.

Minimum Age Maximum Age Gender Healthy Volunteers
50 Years N/A All No
November 1, 2017
November 1, 2022

  • Cognitive impairment as demonstrated by a Memory Performance Index score of 50 or below, or delayed free recall score of 6 or below
  • Stage 2 to 4 on the Functional Assessment Staging Test; if Stage 4, with both impaired cognitive and functional abilities, must have caregiver or legally appointed representative
  • Any medical conditions or medications must be stable
  • Can converse with a coach over a telephone
  • Normal or corrected visual ability and normal color vision
  • Ability to hear adequately
  • Access and ability to use a computer, mobile device, or iPad (with or without assistance)
  • Email address and access to the Internet
  • Speak and write English

  • Neurodegenerative disorder other than Alzheimer's, such as Lewy body dementia or frontotemporal disorder
  • Cognitive impairment primarily caused by cerebrovascular disease, such as stroke or stenosis (vessel narrowing) 
  • Participation in other similar coaching programs
  • Genetic mutation for early-onset familial Alzheimers disease (in PSEN or APP genes) in participant or immediate family (children, siblings, or parents)

Participants will be randomized to receive either coaching plus routine care or routine care only for 2 years. Researchers will compare treatment-related changes in memory, cognitive function, ability to perform activities of daily living, and quality of life. Changes in biological or biochemical measures will also be measured, along with changes in diagnosis, for example, from MCI to Alzheimer's disease.

Name City State Zip Status Primary Contact
Hoag Memorial Hospital Presbyterian
Newport Beach California 92663 Recruiting Deborah Fridman, PsyD

Hoag Memorial Hospital Presbyterian

  • Institute for Systems Biology

Name Role Affiliation
Deborah Fridman, PsyD Study Director Hoag Memorial Hospital Presbyterian
William Shankle, MD Principal Investigator Hoag Memorial Hospital Presbyterian

Name Phone Email
Laura Heim 949-764-8190


Coaching for Cognition in Alzheimer's (COCOA)