Alzheimer's Disease Education and Referral Center

Clinical Evaluation of Florbetapir F 18 (18F-AV-45)

Clinical Evaluation of Florbetapir F 18 (18F-AV-45)

Overall Status: 
Recruiting
Brief Description: 

This study is designed to standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden in subjects participating in other studies, such as longitudinal studies of aging and studies of biomarkers for neurodegenerative diseases.

Patient Qualifications: 
Min AgeMax AgeGenderHealthy Volunteers
18 Years
N/A
Both
Yes
Inclusion Criteria: 

  • At least 18 years of age
  • Ability to tolerate the PET scan procedures

Exclusion Criteria: 

  • Clinically significant hepatic, renal, pulmonary, metabolic, or endocrine conditions
  • Clinically significant cardiovascular disease, such as cardiac surgery or myocardial infarction within the last 4 weeks, unstable angina, significant cardiac arrhythmia or conduction disturbance, uncontrolled high blood pressure
  • History of drug or alcohol abuse within the last year or prior prolonged history of abuse
  • Women of childbearing potential who are not surgically sterile, not refraining from sexual activity or not using reliable methods of contraception; women of childbearing potential must not be pregnant or breastfeeding
  • History of relevant severe drug allergy or hypersensitivity, as determined by investigators
  • Taking of an investigational medication under an FDA IND protocol within the last 30 days
  • Unstable medical comorbidities that pose a potential safety risk to the subject
  • Radiopharmaceutical for imaging or therapy within the past 24 hours prior to the imaging session for this study unless the trial sponsor has approved it

Detailed Description: 

None

Central Contact Information: 

For more information about individual study sites, contact Avid Clinical Operations: call 1-215-298-0700 or e-mail clinicaloperations@avidrp.com.

Locations: 
Map Marker CityStateZip CodeStatusPrimary Contact

Geolocation is 33.4636012, -112.0535987

Banner Health
Phoenix
Arizona
85006
Completed

Geolocation is 33.4636012, -112.0535987

Banner Health
Phoenix
Arizona
85006
Recruiting
602-839-6999

Geolocation is 33.6020658, -112.280129

Banner Sun Health Research Institute
Sun City
Arizona
85351
Completed

Geolocation is 38.5449065, -121.7405167

UC Davis
Davis
California
95618
Recruiting
916-734-5223

Geolocation is 33.6471239, -117.8421325

UC Irvine
Irvine
California
92697
Completed

Geolocation is 34.0502898, -118.2117257

University of Southern California
Los Angeles
California
90033
Recruiting
323-865-9949

Geolocation is 33.78659, -117.8750976

UC Irvine
Orange
California
92868
Completed

Geolocation is 37.7813454, -122.497668

UC San Francisco
San Francisco
California
94121
Completed

Geolocation is 37.7813454, -122.497668

UC San Francisco
San Francisco
California
94121
Recruiting
415-221-4810

Geolocation is 37.7813454, -122.497668

UC San Francisco
San Francisco
California
94121
Recruiting
415-750-2069

Geolocation is 37.7642093, -122.4571623

UC San Francisco Memory Center
San Francisco
California
94143
Completed

Geolocation is 30.3476884, -81.7458845

Mayo Clinic Jacksonville
Jacksonville
Florida
32254
Active, not recruiting

Geolocation is 30.3476884, -81.7458845

Mayo Clinic Jacksonville
Jacksonville
Florida
32254
Recruiting
904-953-7103

Geolocation is 25.8176795, -80.1372757

Mt. Sinai Medical Center
Miami Beach
Florida
33140
Recruiting
305-674-2543

Geolocation is 41.8925085, -87.6161696

Northwestern University
Chicago
Illinois
60611
Recruiting
312-503-1155

Geolocation is 39.06, -94.61

University of Kansas
Kansas City
Kansas
66160
Completed

Geolocation is 39.2962372, -76.5928888

Johns Hopkins University
Baltimore
Maryland
21287
Completed

Geolocation is 39.2962372, -76.5928888

Johns Hopkins University
Baltimore
Maryland
21287
Recruiting
410-955-8433

Geolocation is 42.3652917, -71.0646337

Massachusetts General Hospital
Boston
Massachusetts
02114
Completed

Geolocation is 32.3361632, -90.1565209

University of Mississippi Medical Center
Jackson
Mississippi
39216
Completed

Geolocation is 38.6212468, -90.2526163

Washington University School of Medicine
St. Louis
Missouri
63110
Completed

Geolocation is 36.0038131, -78.9387241

Duke University
Durham
North Carolina
27710
Completed

Geolocation is 36.0937141, -80.3268812

Wake Forest University
Winston-Salem
North Carolina
27104
Completed

Geolocation is 39.9559288, -75.1574567

Jefferson
Philadelphia
Pennsylvania
19107
Completed

Geolocation is 39.9559288, -75.1574567

University of Pennsylvania
Philadelphia
Pennsylvania
19107
Recruiting
215-294-9172

Geolocation is 41.8396817, -71.3883751

Butler Hospital
Providence
Rhode Island
02906
Recruiting
401-455-6403

Geolocation is 35.9113041, -83.8685072

University of Tennessee
Knoxville
Tennessee
37920
Completed

Geolocation is 36.1426398, -86.8001068

Vanderbilt
Nashville
Tennessee
37232
Completed

Geolocation is 32.8798071, -96.7547522

UTSW
Dallas
Texas
75231
Recruiting
214-345-8843

Geolocation is 32.8296623, -96.8511814

UTSW
Dallas
Texas
75235
Recruiting
972-883-3255

Geolocation is 32.8113367, -96.8397899

UTSW
Dallas
Texas
75390
Recruiting
214-648-0499
Lead Sponsor: 
Agency
Avid Radiopharmaceuticals
Collaborator Sponsor: 
Facility Investigators: 
NameRoleAffiliation
Chief Medical Officer
Study Director
Avid Radiopharmaceuticals
Study Contact: 
NamePhoneEmail
Avid Clinical Operations
215-298-0700
Locations
 
 
ClinicalTrials.gov ID 
NCT01518374 (follow link to view full record on ct.gov in new window)
Official Title: 
Clinical Evaluation of Florbetapir F 18 (18F-AV-45)
Study Start Date: 
December 2009
Study End Date: 
December 2015
Enrollment: 
600