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Caregiver Outcomes of Alzheimer's Disease Screening

Recruiting

This randomized controlled trial will measure the risks and benefits of early screening for Alzheimer's disease in terms of its effects on family caregivers. Early diagnosis through screening may enhance the family member's transition to caregiving and reduce caregiver burden by providing an opportunity for the family member to learn about the syndrome, receive interventions, and prepare for the new caregiving role.

Minimum Age Maximum Age Gender Healthy Volunteers
65 Years N/A All No
October 15, 2018
September 30, 2023
3600

Patients:

  • At least one visit to primary care practice within the past year
  • Able to communicate in English

Family Caregivers:

  • Identified by the participant as the person most likely to provide them care if needed
  • Lives with the participant or lives within a 50-mile radius
  • Able to communicate in English

Patients:

  • Diagnosis of Alzheimer's disease
  • Prescription for a cholinesterase inhibitor or memantine
  • Serious mental illness such as bipolar disorder or schizophrenia
  • Permanent residence in a nursing facility
  • Already seen by the Healthy Aging Brain Care Program

Family Members:

  • Non-family member who does not have healthcare power of attorney
  • Serious mental illness such as bipolar disorder or schizophrenia
  • Diagnosis of Alzheimer's disease

Older adult/family member pairs will be randomized into three groups. In the first group, the older adults will be screened for Alzheimer's disease and the results will be disclosed to them, their family member, and their primary care provider. Older adults in the second group will receive the same screening and disclosure. In addition, if they screen positive, they will be referred to an Aging Brain Care (ABC) program for diagnostic evaluation and care. Older adults in the third group will not be screened. At the end of the study, the family members will be assessed for health-related quality of life, caregiving preparedness, and caregiving self-efficacy.

Name City State Zip Status Primary Contact
Eskenazi Hospital
Indianapolis Indiana 46202 Recruiting Malaz Boustani, MD
317-274-9235
mboustan@iupui.edu
IU Health-Primary Care Clinics
Indianapolis Indiana 46202 Recruiting Lev Inger
317-274-9123
levinger@iupui.edu

Indiana University

Name Role Affiliation
Nicole Fowler, PHD Principal Investigator Indiana University

Name Phone Email
Lev Inger, MPH 317-274-9123 levinger@iupui.edu
Shelley Suarez, MSN, RN 317-274-9509 sdsuarez@regenstrief.org

NCT03300180

Caregiver Outcomes of Alzheimer's Disease Screening