Alzheimer's Disease Education and Referral Center

Clinical Trials

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Alzheimer's Disease Clinical Trials Search Results

Your search identified 156 trials:

  1. Purpose: To test the relationship between tau pathology and the brain imaging agent 18F-AV-1451 in people near the end of life.
    Category(s): Biomarkers and Brain Imaging
  2. Purpose: To identify reliable methods for tracking corticobasal degeneration and progressive supranuclear palsy.
    Category(s): Non-Alzheimer's Dementias, Biomarkers and Brain Imaging, Healthy Volunteers
  3. Purpose: To evaluate changes in the protein tau in the brain of people at different stages of Alzheimer's disease and in healthy volunteers.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  4. Purpose: To evaluate ABBV-8E12 in older adults with early Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  5. Purpose: To test the ACI-24 vaccine in adults with Down syndrome.
    Category(s): Drugs and Hormones
  6. Purpose: To build a clinical research consortium to test new treatments for people with frontotemporal lobar degeneration.
    Category(s): Non-Alzheimer's Dementias
  7. Purpose: To examine the impact of a combined cognitive training and aerobic exercise intervention in sedentary older adults.
    Category(s): Cognitive Training/Stimulation, Exercise, Healthy Volunteers
  8. Purpose: To evaluate the safety and tolerability of allopregnanolone, a naturally occurring brain steroid, in people with mild cognitive impairment or mild Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  9. Purpose: To compare two intervention strategies for reducing emotional and cardiovascular disease risk in Alzheimer's caregivers.
    Category(s): Caregivers, Healthy Volunteers
  10. Purpose: To identify the genes that cause late-onset Alzheimer's disease.
    Category(s): Genetics
  11. Purpose: To determine the relationships among clinical, cognitive, imaging, genetic, and biomarker characteristics of the entire spectrum of Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Biomarkers and Brain Imaging, Healthy Volunteers
  12. Purpose: To study how multiple family members provide care for a person with Alzheimer's disease.
    Category(s): Caregivers
  13. Purpose: To enroll individuals who are interested in learning about and possibly participating in Alzheimer's prevention clinical studies and trials in a national registry.
    Category(s): Mild Cognitive Impairment, Caregivers, Healthy Volunteers
  14. Purpose: To learn about the possible benefits of aerobic exercise for individuals at risk of developing Alzheimer's disease.
    Category(s): Exercise
  15. Purpose: To test ALZT-OP1 as a treatment for cognitive and functional decline in people with early-stage Alzheimer's disease.
    Category(s): Drugs and Hormones
  16. Purpose: To identify older adults with diagnosed or suspected Alzheimer's disease who are interested in participating in a drug trial.
    Category(s): Drugs and Hormones
  17. Purpose: To test whether an anti-amyloid investigational drug, solanezumab, can slow memory and cognitive decline in older individuals who do not yet show symptoms of Alzheimer's disease cognitive impairment or dementia.
    Category(s): Drugs and Hormones, Healthy Volunteers
  18. Purpose: To test methylphenidate (Ritalin®) as a treatment for clinically significant apathy in people with Alzheimer's disease.
    Category(s): Drugs and Hormones, Behavior/Symptom Management
  19. Purpose: To understand how an experimental computer program can affect cognition and attention in older adults with age-related cognitive decline.
    Category(s): Cognitive Training/Stimulation
  20. Purpose: To evaluate the ability of sounds played during slow-wave sleep to enhance sleep and memory in older adults.
    Category(s): Mild Cognitive Impairment, Cognitive Training/Stimulation
  21. Purpose: To test the experimental drug AVP-786 as a treatment for agitation in people with Alzheimer's dementia.
    Category(s): Drugs and Hormones, Behavior/Symptom Management
  22. Purpose: To assess the efficacy and safety of AZD3293 as a possible treatment for early Alzheimer´s disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  23. Purpose: To study the use of a nutraceutical drink to improve cognition in people with mild cognitive impairment and prediabetes.
    Category(s): Diet and Dietary Supplements, Mild Cognitive Impairment
  24. Purpose: To compare the impact of a walking program, computer-based cognitive training program, and both programs in adults with mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Cognitive Training/Stimulation, Exercise, Healthy Volunteers
  25. Purpose: To determine whether treatment with benfotiamine, a dietary supplement, minimizes cognitive decline in older adults with amnestic mild cognitive impairment or mild Alzheimer's disease.
    Category(s): Diet and Dietary Supplements, Mild Cognitive Impairment
  26. Purpose: To test the experimental drug BI 409306 in people with Alzheimer's disease or schizophrenia and in healthy volunteers.
    Category(s): Drugs and Hormones, Healthy Volunteers
  27. Purpose: To test the experimental drug BI 409306 in people with cognitive impairment due to Alzheimer's disease.
    Category(s): Drugs and Hormones
  28. Purpose: To test the experimental drug BI 409306 in people with early Alzheimers disease.
    Category(s): Drugs and Hormones
  29. Purpose: To evaluate the safety and tolerability of BIIB076 in cognitively normal older adults and older adults with Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones, Healthy Volunteers
  30. Purpose: To test the safety and action of the drug bisnorcymserine in healthy older volunteers.
    Category(s): Drugs and Hormones, Healthy Volunteers
  31. Purpose: To study brain changes in veterans with traumatic brain injury or post traumatic stress disorder, with and without mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Biomarkers and Brain Imaging, Healthy Volunteers
  32. Purpose: To compare the brain's removal of waste after a good night's sleep and after sleep deprivation.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  33. Purpose: To investigate brain changes associated with playing a race-car video game in older adults.
    Category(s): Cognitive Training/Stimulation, Biomarkers and Brain Imaging, Healthy Volunteers
  34. Purpose: To enroll people interested in participating in brain health research in an ongoing online registry.
    Category(s): Mild Cognitive Impairment, Caregivers, Healthy Volunteers
  35. Purpose: To test whether two investigational drugs, CAD106 and CNP520, can prevent or delay Alzheimer's symptoms in people at high risk.
    Category(s): Drugs and Hormones, Healthy Volunteers
  36. Purpose: To learn more about cerebral autosomal dominant arteriopathy with subcortical infarct (CADASIL).
    Category(s): Non-Alzheimer's Dementias
  37. Purpose: To compare the effects of two hypertension medications on the brains of people with high blood pressure and impaired executive functioning.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  38. Purpose: To investigate the effect of candesartan, a blood pressure medication, on cognitive function in people with mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  39. Purpose: To evaluate a care model for people with dementia and their family caregivers.
    Category(s): Caregivers
  40. Purpose: To test the effectiveness of a technology-based support program for culturally diverse family caregivers of people with Alzheimer's.
    Category(s): Mild Cognitive Impairment, Caregivers, Healthy Volunteers
  41. Purpose: To characterize the biological mechanisms contributing to cognitive impairment and decline in older adults with depression.
    Category(s): Biomarkers and Brain Imaging
  42. Purpose: To determine if stopping certain medications for Alzheimer's disease will cause worsened cognition, functioning, or behavior in veterans with advanced dementia.
    Category(s): Drugs and Hormones
  43. Purpose: To standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  44. Purpose: To determine the efficacy of coconut oil as a possible treatment for mild to moderate Alzheimer's disease.
    Category(s): Diet and Dietary Supplements
  45. Purpose: To test the impact of cognitive and/or exercise training on cognition in older adults with mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Cognitive Training/Stimulation, Exercise
  46. Purpose: To validate several novel cognitive tasks and correlate them with Alzheimer's disease biomarkers in people who are cogntitively normal or have mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Biomarkers and Brain Imaging, Healthy Volunteers
  47. Purpose: To evaluate the effects of cognitive rehabilitation and transcranial electrical stimulation in adults who are cognitively normal or experiencing cognitive dysfunction.
    Category(s): Cognitive Training/Stimulation, Healthy Volunteers
  48. Purpose: To test the effectiveness of a computerized cognitive (thinking) training program in people with mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Cognitive Training/Stimulation
  49. Purpose: To assess the use of cognitive training before surgery in patients at high risk for delirium.
    Category(s): Surgery, Cognitive Training/Stimulation
  50. Purpose: To examine the impact on older adults of learning the results of amyloid brain imaging.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  51. Purpose: To test Internet-based speech and language therapy for people with primary progressive aphasia, Alzheimer's disease, behavioral variant frontotemporal dementia (bvFTD), or related conditions.
    Category(s): Non-Alzheimer's Dementias, Cognitive Training/Stimulation
  52. Purpose: To evaluate the safety and tolerability of crenezumab in older adults with mild to moderate Alzheimer's disease.
    Category(s): Drugs and Hormones
  53. Purpose: To test the experimental drug crenezumab in people with early to mild Alzheimer's disease.  
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  54. Purpose: To test the clinical benefits of curcumin, a compound isolated from turmeric root, and a yoga-based physical exercise program in individuals with early memory problems.
    Category(s): Diet and Dietary Supplements, Mild Cognitive Impairment, Exercise
  55. Purpose: To investigate the effects of a cycling exercise program on cognition and hippocampal volume in older adults with Alzheimer's disease.
    Category(s): Exercise
  56. Purpose: To assess the effect of a cocoa-derived dietary supplement on cognitive function related to the dentate gyrus.
    Category(s): Diet and Dietary Supplements, Healthy Volunteers
  57. Purpose: To test how different types of meals affect Alzheimer's biomarkers in healthy older adults with and without the APOE E4 genotype.
    Category(s): Diet and Dietary Supplements, Biomarkers and Brain Imaging, Healthy Volunteers
  58. Purpose: To test two dietary interventions in overweight, middle-aged individuals with subjective memory complaints.
    Category(s): Diet and Dietary Supplements, Mild Cognitive Impairment
  59. Purpose: To study the effect on cognition of a modified Atkins diet in older adults with mild cognitive impairment or early Alzheimer's disease.
    Category(s): Diet and Dietary Supplements, Mild Cognitive Impairment
  60. Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  61. Purpose: To evalute the safety and pharmacokinetics of a transdermal donepezil patch compared to pills.
    Category(s): Drugs and Hormones, Healthy Volunteers
  62. Purpose: To determine if the drug memantine can improve learning and memory in adolescents and young adults with Down syndrome.
    Category(s): Biomarkers and Brain Imaging, Drugs and Hormones, Healthy Volunteers
  63. Purpose: To test the safety and efficacy of dronabinol to treat agitation in older adults with Alzheimer's.
    Category(s): Drugs and Hormones
  64. Purpose: To evaluate the safety, tolerability, and pharmacodynamics of E2027 in healthy participants.
    Category(s): Drugs and Hormones, Healthy Volunteers
  65. Purpose: To study vascular risk factors that cause memory and thinking problems and ways to control these risk factors.
    Category(s): Non-Alzheimer's Dementias, Mild Cognitive Impairment
  66. Purpose: To determine whether, compared with usual anesthetic care, an EEG-guided anesthesia protocol can prevent delirium after surgery.
    Category(s): Surgery
  67. Purpose: To evaluate the effects of surgical anesthesia on cognition and certain Alzheimer's disease biomarkers in older adults who undergo surgery.
    Category(s): Surgery, Biomarkers and Brain Imaging
  68. Purpose: To determine if the presence of beta-amyloid plaques in the brains of non-demented patients before hip or knee replacement surgery predicts cognitive decline after surgery.
    Category(s): Surgery, Biomarkers and Brain Imaging
  69. Purpose: To examine the sensitivity of functional MRI to detect brain changes in healthy older adults at genetic risk for Alzheimer's disease who take donepezil (Aricept).
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  70. Purpose: To evaluate treatment of early Alzheimer's disease with the experimental drug aducanumab (BIIB037).
    Category(s): Drugs and Hormones
  71. Purpose: To evaluate treatment of early Alzheimer's disease with the experimental drug aducanumab (BIIB037).
    Category(s): Drugs and Hormones
  72. Purpose: To test the effect of noninvasive brain stimulation on older adults' ability to navigate.
    Category(s): Mild Cognitive Impairment, Medical Devices, Healthy Volunteers
  73. Purpose: To test the effects of the antidepressant escitalopram on levels of amyloid beta in the cerebrospinal fluid of cognitively normal older adults.
    Category(s): Drugs and Hormones, Healthy Volunteers
  74. Purpose: To evaluate the effects of physical exercise on cognition, functional status, brain atrophy, blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
    Category(s): Mild Cognitive Impairment, Exercise
  75. Purpose: To evaluate the efficacy and safety of the experimental drug gantenerumab as a possible treatment for people with mild Alzheimer disease.
    Category(s): Drugs and Hormones
  76. Purpose: To identify people interested in participating in research studies or clinical trials based in part on their genetic background.
    Category(s): Healthy Volunteers, Genetics
  77. Purpose: To learn more about biomarkers and their relationship to aging.
    Category(s): Healthy Volunteers
  78. Purpose: To learn more about the genetic causes of movement disorders and dementias.
    Category(s): Non-Alzheimer's Dementias, Healthy Volunteers, Genetics
  79. Purpose: To establish the safety and pharmacokinetics of grape seed extract and to test its cognitive effects in people with Alzheimer's disease.
    Category(s): Diet and Dietary Supplements
  80. Purpose: To learn about health care use and costs for people with mild cognitive impairment or early-stage Alzheimer’s disease.
    Category(s): Mild Cognitive Impairment
  81. Purpose: To improve the cognitive and mental health of Alzheimer's disease caregivers by testing a mobile app that provides support and assistance.
    Category(s): Caregivers
  82. Purpose: To implement and evaluate a home-based dementia care coordination program called MIND at Home-Plus.
    Category(s): Caregivers
  83. Purpose: To evaluate the level of two antioxidants in the brain as humans with and without Alzheimer's disease get older.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  84. Purpose: To assess the impact of amyloid PET imaging on outcomes in patients with mild cognitive impairment or dementia of uncertain origin.
    Category(s): Mild Cognitive Impairment, Biomarkers and Brain Imaging
  85. Purpose: To study how the brain functions when it performs explicit memory tasks and how this changes as a function of aging.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  86. Purpose: To use brain imaging to study tau accumulation in people with Alzheimer's disease and in people with normal cognition.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  87. Purpose: To test the use of mobile health devices in helping older adults independently walk to improve cognitive health.
    Category(s): Exercise, Healthy Volunteers
  88. Purpose: To test the effects of fast-acting intranasal insulin on cognition and daily function in people with Alzheimer's disease or mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  89. Purpose: To examine cognitive and neural biomarkers in adults who are overweight or obese and younger than 50.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  90. Purpose: To compare two forms of diet and their effects on insulin resistance, weight, and brain chemicals related to Alzheimer's disease.
    Category(s): Diet and Dietary Supplements
  91. Purpose: To evaluate the use of intranasal glulisine in people with amnestic mild cognitive impairment or mild Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  92. Purpose: To study the use of ITI-007 to treat agitation in people with dementia, including Alzheimer's disease.
    Category(s): Drugs and Hormones, Behavior/Symptom Management
  93. Purpose: To further define the neurological and linguistic deterioration in primary progressive aphasia.
    Category(s): Non-Alzheimer's Dementias
  94. Purpose: To test the use of levetiracetam, an anticonsulvant, to control seizures in people with Alzheimer's disease.
    Category(s): Drugs and Hormones
  95. Purpose: To evaluate the effect of exercise and healthy living education on brain health, cognition, and physical function in older adults with cognitive concerns.
    Category(s): Exercise, Healthy Volunteers
  96. Purpose: To learn about thinking and behavior in families in which one or more relatives has a genetic mutation associated with frontotemporal dementia.
    Category(s): Non-Alzheimer's Dementias, Biomarkers and Brain Imaging, Healthy Volunteers
  97. Purpose: To evaluate the effect of LY3002813 in people with mild cognitive impairment or Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  98. Purpose: To study the safety and tolerability of the experimental drug LY3303560.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones, Healthy Volunteers
  99. Purpose: To evaluate the feasibility of a Mediterranean diet in older adults.
    Category(s): Diet and Dietary Supplements, Mild Cognitive Impairment, Healthy Volunteers
  100. Purpose: To determine if following a Mediterranean diet resulting in weight loss improves cognition in obese older adults.
    Category(s): Diet and Dietary Supplements, Healthy Volunteers
  101. Purpose: To examine if and how brain scans can predict decline in memory and executive functioning in older adults after total knee replacement surgery.
    Category(s): Surgery, Biomarkers and Brain Imaging, Healthy Volunteers
  102. Purpose: To study how women undergoing breast cancer treatment may develop brain changes related to the development of mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Biomarkers and Brain Imaging, Healthy Volunteers
  103. Purpose: To test the effects of the MIND diet on cognitive decline in seniors without cognitive impairment.
    Category(s): Diet and Dietary Supplements, Healthy Volunteers
  104. Purpose: To evaluate a home-based dementia care intervention for people with dementia and their family caregivers.
    Category(s): Caregivers
  105. Purpose: To study how genetics influences memory by analyzing adults' performance on a web-based memory test.
    Category(s): Healthy Volunteers, Genetics
  106. Purpose: To examine the effects on age-related cognitive decline of mindfulness-based stress reduction, aerobic exercise, and their combination, compared with a health discussion group.
    Category(s): Cognitive Training/Stimulation, Exercise, Healthy Volunteers
  107. Purpose: To learn about the possible benefits of movement and music therapy in older adults with dementia.
    Category(s): Exercise
  108. Purpose: To characterize the natural history of disease in people who carry a repeat expansion in the C9ORF72 gene, which causes amyotrophic lateral sclerosis and frontotemporal dementia.
    Category(s): Non-Alzheimer's Dementias, Biomarkers and Brain Imaging
  109. Purpose: To evaluate nelotanserin as a possible treatment for REM sleep behavior disorder in people with dementia with Lewy bodies.
    Category(s): Non-Alzheimer's Dementias, Drugs and Hormones
  110. Purpose: To test the experimental drug nelotanserin for the treatment of visual hallucinations in people with Lewy body dementia.
    Category(s): Non-Alzheimer's Dementias, Drugs and Hormones
  111. Purpose: To validate the online cognitive measures used by the Brain Health Registry.
    Category(s): Mild Cognitive Impairment, Healthy Volunteers
  112. Purpose: To validate Neurotrack's visual paired comparison task, aimed at early detection and monitoring of memory impairment.
    Category(s): Mild Cognitive Impairment, Biomarkers and Brain Imaging
  113. Purpose: To test the safety and efficacy of the drug nilotinib in people with mild to moderate Alzheimer's disease.
    Category(s): Drugs and Hormones
  114. Purpose: To determine if a worsened sense of smell can identify older people who might benefit from treatment with the Alzheimer's drug donepezil.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  115. Purpose: To evaluate the effect of icosapent ethyl in veterans at increased risk of Alzheimer's.
    Category(s): Diet and Dietary Supplements, Healthy Volunteers
  116. Purpose: To examine the effectivness of an established counseling approach and a variation of it for veterans with dementia and their family caregivers who have high levels of stress. 
    Category(s): Caregivers, Behavior/Symptom Management
  117. Purpose: To compare brain-wave patterns in older patients who have memory and thinking problems after surgery with brain-wave patterns in patients without such problems.
    Category(s): Surgery, Healthy Volunteers
  118. Purpose: To test a model of palliative care consultation for hospitalized patients with advanced dementia and their family caregivers.
    Category(s): Caregivers
  119. Purpose: To compare usual care to palliative care for adults with Parkinson's disease and related disorders.
    Category(s): Non-Alzheimer's Dementias, Caregivers
  120. Purpose: To assess the effect on cognition of increasing physical activity using a body-worn sensor in older adults.
    Category(s): Exercise, Healthy Volunteers
  121. Purpose: To compare the impact on cogition and psychosocial well-being of piano training, compared with computer training and no training, in older adults.
    Category(s): Cognitive Training/Stimulation, Healthy Volunteers
  122. Purpose: To test the drug pimavanserin (Nuplazid™) as a treatment for agitation and aggression in adults with Alzheimer's disease.
    Category(s): Drugs and Hormones, Behavior/Symptom Management
  123. Purpose: To test the safety and efficacy of the experimental drug piromelatine in people with mild Alzheimer's dementia.
    Category(s): Drugs and Hormones
  124. Purpose: To determine if drinking pomegranate juice benefits cognitive abilities in middle-aged and older adults without dementia.
    Category(s): Diet and Dietary Supplements, Mild Cognitive Impairment, Healthy Volunteers
  125. Purpose: To evaluate Posiphen® in older adults with early-stage Alzheimer’s disease.
    Category(s): Drugs and Hormones
  126. Purpose: To examine the effects of an intervention for caregivers of people with dementia.
    Category(s): Caregivers, Behavior/Symptom Management
  127. Purpose: To test the use of a video about advance care planning for nursing home residents.
  128. Purpose: To test a novel, integrative exercise program in older veterans with dementia.
    Category(s): Exercise, Behavior/Symptom Management
  129. Purpose: To test the effects of transcranial direct current stimulation on memory in people with mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Medical Devices, Healthy Volunteers
  130. Purpose: To evaluate the effect of the drug rasagiline on brain metabolism in people with mild to moderate Alzheimer's disease.
    Category(s): Drugs and Hormones
  131. Purpose: To evaluate the effects of reasoning training combined with transcranial direct current stimulation (tDCS) in people with memory complaints.
    Category(s): Mild Cognitive Impairment, Medical Devices, Cognitive Training/Stimulation
  132. Purpose: To use magnetic resonance imaging to investigate brain function and connections in healthy adults.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  133. Purpose: To determine if repetitive transcranial magnetic stimulation (rTMS) can effectively treat apathy in people with Alzheimer's dementia.
    Category(s): Medical Devices, Behavior/Symptom Management
  134. Purpose: To determine if repetitive transcranial magnetic stimulation improves cognitive function in people with mild to moderate cognitive impairment or dementia.
    Category(s): Medical Devices
  135. Purpose: To evaluate a program for decreasing caregiver distress and strain after transitioning a cognitively impaired relative to long-term care.
    Category(s): Caregivers, Healthy Volunteers
  136. Purpose: To test the safety and effectiveness of the drug riluzole for treating mild Alzheimer's disease.
    Category(s): Biomarkers and Brain Imaging, Drugs and Hormones
  137. Purpose: To establish a bank of blood, cerebrospinal fluid, imaging, and clinical data to be used in Alzheimer's disease research.
    Category(s): Non-Alzheimer's Dementias, Mild Cognitive Impairment, Biomarkers and Brain Imaging, Healthy Volunteers
  138. Purpose: To test the drug RVT-101 in people with dementia with Lewy bodies.
    Category(s): Non-Alzheimer's Dementias, Drugs and Hormones
  139. Purpose: To test the effects of sargramostim in people with mild cognitive impairment due to Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  140. Purpose: To examine the relationship between sleep-disordered breathing and Alzheimer's disease in cognitive normal older adults.
    Category(s): Medical Devices, Biomarkers and Brain Imaging, Healthy Volunteers
  141. Purpose: To study memory and aging in healthy older adults.
    Category(s): Biomarkers and Brain Imaging, Healthy Volunteers
  142. Purpose: To test the experimental drug SUVN-502 as a treatment for moderate Alzheimer's disease in people taking donepezil and memantine.
    Category(s): Drugs and Hormones
  143. Purpose: To assess the safety, tolerability, and pharmacokinetics of the experimental drug TAK-071 for mild cognitive impairment and mild Alzheimer's disease.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones, Healthy Volunteers
  144. Purpose: To evaluate a new radioactive compound used in positron emission tomography scans to identify tau tangles.
    Category(s): Biomarkers and Brain Imaging
  145. Purpose: To test an Internet-based education program for dementia caregivers.
    Category(s): Caregivers, Healthy Volunteers, Behavior/Symptom Management
  146. Purpose: To determine if the blood-pressure medication telmisartan might help prevent Alzheimer's disease in African Americans.
    Category(s): Drugs and Hormones
  147. Purpose: To determine whether duloxetine (Cymbalta®) can improve cognition in individuals with mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Drugs and Hormones
  148. Purpose: To investigate the effect of transcranial alternating current stimulation on sleep and cognitive performance in older adults.
    Category(s): Mild Cognitive Impairment, Medical Devices, Healthy Volunteers
  149. Purpose: To study the effects of transcranial direct current stimulation during language therapy in people with primary progressive aphasia.
    Category(s): Non-Alzheimer's Dementias, Medical Devices
  150. Purpose: To test lithium as a treatment for psychosis and agitation in older adults with Alzheimer's disease.
    Category(s): Drugs and Hormones, Behavior/Symptom Management
  151. Purpose: To determine if oxaloacetate is safe and tolerable in people with Alzheimer's disease.
    Category(s): Drugs and Hormones
  152. Purpose: To test the effectiveness of using assessments to diagnose Alzheimer's disease in Hispanic/Latino adults with mild cognitive impairment or Alzheimer's. 
    Category(s): Mild Cognitive Impairment, Healthy Volunteers
  153. Purpose: To study the effects of an education and skill-building intervention on family caregivers of veterans with dementia.
    Category(s): Caregivers, Healthy Volunteers
  154. Purpose: To identify brain changes in adults with mild cognitive impairment who engage in vision-based speed of processing cognitive training.
    Category(s): Mild Cognitive Impairment, Cognitive Training/Stimulation
  155. Purpose: To evaluate the feasibility of a water-based exercise program with cognitive training to improve memory in veterans with mild cognitive impairment.
    Category(s): Mild Cognitive Impairment, Cognitive Training/Stimulation, Exercise
  156. Purpose: To assess the experimental drug Xanamem® in older adults with mild Alzheimer's disease.
    Category(s): Drugs and Hormones