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Find more clinical trials

Down Syndrome Clinical Trials Network-Study of Alzheimer's Disease

Start: June 30, 2019
End: December 2026
Enrollment: 270

What Is This Study About?

Adults with Down syndrome are at increased risk for Alzheimer's disease as they age. The Longitudinal Investigation for the Enhancement of Down Syndrome Research (LIFE-DSR) is an observational study to understand the cognitive and behavioral changes and health issues in adults with Down syndrome as they progress toward Alzheimer's disease. Over two years, the researchers will assess changes in cognition, behavior, function, and health in people with Down syndrome. Blood will also be collected to find biomarkers that could help diagnose and track disease progression.

Do I Qualify To Participate in This Study?

Minimum Age: 25 Years

Maximum Age: N/A

Must have:

  • Diagnosis of Down syndrome
  • Study partner who has regular interaction, can participate in annual clinic visits, and can respond to questions about the participant
  • Participant and study partner must be capable of reliably completing study assessments

Must NOT have:

  • Participants and study partners who are not able to complete trial procedures or adhere to the schedule of study assessments

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Who Is the General Study Contact?

For more information about this study or study sites, visit About LIFE-DSR.

Study Contact
Tashia Harris, MS
Lois Kelly

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Arizona
Barrow Neurological Institute
Phoenix, AZ 85013
Recruiting
Sandy Quintanilla
California
University California Irvine
Irvine, CA 92697
Recruiting
Kelly Kilday
University of California, San Diego
La Jolla, CA 92093
Recruiting
Bailey Hoffman
Georgia
Emory University
Atlanta, GA 30322
Recruiting
Robin Vinson
Illinois
Rush University Medical Center
Chicago, IL 60612
Recruiting
Melissa Baer
Advocate Health
Park Ridge, IL 60068
Recruiting
Nickolas Armijo
Kansas
Kansas University Medical Center
Fairway, KS 66205
Recruiting
Kayla Meyer
Kentucky
University Of Kentucky
Lexington, KY 40536
Recruiting
Roberta Davis
Maryland
Kennedy Krieger Institute
Baltimore, MD 21205
Recruiting
Research Trials
Massachusetts
Massachusetts General Hospital
Boston, MA 02114
Recruiting
Sajani Clerk
Massachusetts General Hospital
Charlestown, MA 02129
Recruiting
Gabriela Leka
North Carolina
Duke University Medical Center
Durham, NC 27710
Recruiting
Gretchen Nichting
Ohio
Cincinnati Children's Hospital Medical Center
Cincinnati, OH 45229
Recruiting
Kellie Voth
Case Western Reserve University
Cleveland, OH 044106
Recruiting
Melissa Stasko

Who Sponsors This Study?

Lead: LuMind IDSC Foundation

Collaborator Sponsor

  • Alzheimer's Disease Cooperative Study (ADCS)

Source: ClinicalTrials.gov ID: NCT04149197

alzheimers.gov

An official website of the U.S. government, managed by the National Institute on Aging at the National Institutes of Health