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Find more clinical trials

Mild Cognitive Impairment in Breast Cancer

Start: June 2013
End: December 2019
Enrollment: 120

What Is This Study About?

This observational study will examine changes in brain-region size, shape, and activity that occur in women with breast cancer and how those changes relate to the development of mild cognitive impairment. Three groups will be compared: women with breast cancer who will undergo hormonal therapy with or without chemotherapy, women with breast cancer who will undergo no therapy or radiation therapy, and healthy female volunteers.

Do I Qualify To Participate in This Study?

Minimum Age: 40 Years

Maximum Age: 70 Years

Must have:

  • Women at any stage of breast cancer without brain metastasis who have undergone surgery (healthy volunteers also accepted)
  • Cognitively normal based on annual examinations done as part of the NIA Alzheimer's Disease Research Centers (ADRC) program
  • Recruited from the Northwestern University ADRC Clinical Core

Must NOT have:

  • Significant medical, neurologic, or psychiatric illness such as major depression, schizophrenia, attention deficit hyperactivity disorder, autism, Alzheimer's disease or other dementia, obsessive-compulsive disorder, or post-traumatic stress disorder
  • Inventory of Depressive Symptomatology-Self Report (IDS-SR) score of 30 or higher
  • Brain surgery or head injury, previous head injury, or condition requiring neurosurgical procedures
  • Ineligibility for magnetic resonance imaging, including but not limited to medical implants or devices, potential metal in the body, claustrophobia, or permanent makeup
  • Consumption of neuropsychiatric or illicit drugs that would affect cognition
  • Individuals with a history of breast cancer will be excluded from the healthy control group.
  • Pregnancy

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: Northwestern University

Collaborator Sponsor

  • National Institute of Nursing Research (NINR)

Source: ClinicalTrials.gov ID: NCT01949376

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