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Zhi-Xin YUAN

Zhi-Xin Yuan, Ph.D.,
Title: Senior Research Assistant (Chemist)
Office(s): Diabetes Section (DS)
Phone Number: 301-594-1594
Email Address: yuanz2@mail.nih.gov

Biography

Dr. Yuan received her B.Sc. degree in Analytical Chemistry from Shengyang Pharmaceutical University (China) and her Ph.D. in Biochemistry from University of London (UK). Dr. Yuan worked as a principal scientist at Palatin Technology and study director and principal investigator at Quest Pharmaceutical Services. Her expertise includes metabolite structure elucidation and quantitation using tandem LC-MS with over 25 years of experience in bioanalysis. Dr. Yuan’s current research focuses on the development and application of tandem mass spectrometry methodologies in the lipidomics field for biomarker discovery, better understanding of disease mechanisms, and nutrition assessment. She led the development and validation of a UPLC-MS/MS method for simultaneous determination of 57 targeted oxylipins and 10 mono- and polyunsaturated fatty acid in plasma, and used mass spectrometry to identify endogenous mediators that were predicted by our group to be abundant in human skin.