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Marilyn MILLER

Marilyn Miller
Title: Program Officer
Office(s): Division of Neuroscience (DN)
Phone Number: 301-496-9350
Email Address: millerm@nia.nih.gov

Biography

Marilyn Miller, Ph.D. began as Program Director for the Genetics of Alzheimer's Disease, Tau, and Hormone Research portfolios at the National Institute on Aging (NIA) in 2000.  As Program Director for the Genetics of Alzheimer’s Disease, a major component of her portfolio is the Alzheimer’s Disease Sequencing Project (ADSP). The ADSP is an initiative announced in 2012 to fight Alzheimer’s disease (AD). The Project emphasizes generation and analysis of sequence data from large AD cohorts including several diversity sample sets and a large family based study. The Project includes two major AD genetics consortia, the NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS); the Genomics Center for Alzheimer’s Disease at the University of Pennsylvania; the National Cell Repository for Alzheimer’s Disease (NCRAD); several large scale sequencing centers; a collaboration with IBM-Watson; and numerous cooperative agreements that fund all Phases of the ADSP. Dr. Miller is involved in all aspects of the ADSP, including monitoring and assessing progress, coordinating numerous projects, and implementing policies related to data deposition and release of human sequence data, and strategic planning. Before joining NIH, she held joint faculty appointments in the Departments of Obstetrics and Gynecology, Experimental Medicine, and Anatomy at McGill University, Montreal, Quebec, Canada. In addition to genetics and the etiology of Alzheimer’s disease, her research interests have included: reproductive biology, reproductive aging and hormone regulation; age-related changes and gene regulation in neurotransmitter systems; and neuropeptide biosynthesis and processing, neuropharmacology, and neurodegeneration. She received a bachelor’s degree from Marquette University, Milwaukee; a master’s degree in Biology at Loyola University of Chicago; and a Ph.D. in Anatomy from Loyola University of Chicago, Stritch School of Medicine. She did a postdoctoral fellowship in reproductive biology at Case Western University and a sabbatical in endocrine-related molecular biology at the University of Colorado. Dr. Miller has published numerous peer-reviewed manuscripts, reviews, and book chapters.  She has served on a number of NIA and NIH-wide committees and work groups and was the first chair of the NIH Program Leadership committee, which she was instrumental in developing.   

Portfolio

  • Studies to identify genetic loci associated with inherited early onset as well as late onset forms of these diseases
  • Studies to understand epigenetic contributions to Alzheimer’s diseaseand related dementias

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