Skip to main content

Vikas Kumar

Dr Vikas Kumar
Title: NIA
Office(s): Cardiac Function Section (CFS)
Email Address: vikaskumar.kumar@nih.gov

Biography

Dr. Vikas Kumar received Ph.D. from Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, India in February 2019 working in a laboratory of Dr. CC. Kartha. During his doctoral tenure, he explored the molecular basis of metabolic remodeling in cardiac hypertrophy and heart failure. He examined in male Wistar rats, the metabolic changes associated with cardiac hypertrophy induced by long-term pressure overload in old age and related the alterations to transitions in mitochondrial transporters and mitochondrial function.

To explore cardiovascular biology further, in November 2019, Dr. Kumar joined as a postdoctoral fellow the Laboratory of Cardiovascular Sciences (LCS) of the National Institute of Aging (NIA). There, under the supervision of Dr. Edward G. Lakatta and in collaboration with Dr. Ranjan Sen, NIA, IRP and Dr. Luigi Adamo from Johns Hopkins University School of Medicine, Dr Kumar is exploring the immunological signatures of mice with cardiac-selective overexpression of adenylyl cyclase type 8 (TGAC8) . These animals are characterized by a unique pattern of cardiac adaptation to injury. Dr Kumar is testing the hypothesis that these adaptive responses might be driven or modulated by the immune system. He is pursuing a mechanistic approach, with the vision that to develop novel immunomodulating therapies for the treatment of cardiovascular disease, it is necessary to gain a deeper mechanistic understanding of the relationship between the immune system and myocardial physiopathology.