Dr. Pragati Katiyar coordinates several programs funded through the Cellular Senescence Network (SenNet). SenNet is a National Institute of Health (NIH) Common Fund program. The Common Fund programs are trans-NIH programs that are designed to address emerging high priority scientific opportunities and challenges that no single NIH Institute or Center (IC) can address on its own.
SenNet program is an effort to comprehensively identify and characterize the differences in senescent cells across various states of human health, and across the lifespan. Currently, SenNet has funded eight programs under Tissue Mapping Center (TMC) to map senescent cells among healthy human tissues, seven Technology Development Applications (TDA) programs to develop new tools and technologies to identify senescent cells, and one consortium and data coordinating center program.
Previously, Dr. Katiyar had led the evaluation of the research portfolio at the NIA’s Office of Portfolio, Analysis, and Evaluation, where through her analytical endeavors she was able to evaluate if a funding mechanism was successful in enriching their work force by attracting new investigators to that field (NTF) from other disciplines irrespective of their career stage. She had also published a peer reviewed publication on this evaluation methodology.
Prior to joining the NIA, she had worked at the National Cancer Institute on the “Ras Initiative” started by Dr. Harold Varmus to better understand mutant RAS protein that is mutated in 95% of all pancreatic cancers and also at the National Health Lung Blood Institute as a Scientific Program Manager in their HIV/AIDS program.
Dr. Katiyar had received her Ph.D. in Tumor Biology from the Lombardi Cancer Center at Georgetown University, Washington, DC where she had investigated molecular mechanisms involved in the BRCA1 (tumor suppressor) inhibition of progesterone receptor signaling to prevent breast cancer. She completed her postdoctoral work at the Thomas Jefferson University, where she studied molecular mechanisms involved in the migration and invasion of melanoma cells. During her tenure at the Thomas Jefferson University, she served as a president of Jefferson Postdoctoral Association and had worked to enhance the first-hand experience of international fellows entering the country for the first time. At the same time, she had also written articles on various career development options available beyond academia for the postdoctoral fellows trying to transition to a non-academic career.