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Max Guo
Title: Health Scientist Administrator
Office(s): Division of Aging Biology (DAB)
Phone Number: 301-402-7747
Email Address:


Max Guo, Ph.D., is the Chief of the Cell Biology Branch, Division of Aging Biology at NIA. Trained as a molecular biologist and biochemist, he obtained a Ph.D. in Biochemistry on study of RNA splicing with Dr. Alan Lambowitz from the Ohio State University in 1992. He did his postdoctoral training on oncogenes with Dr. J. Michael Bishop at University of California at San Francisco. Before joining NIH as a Program Officer in 2002, he was an Assistant Professor of Cancer Biology at the Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins Medical School. He was a Program Officer of Genetics and Genomics at National Institute on Alcohol Abuse and Alcoholism and National Heart, Lung and Blood Institute from 2002 to 2007. From 2008-2011, he was the Deputy Director of the Division of Metabolism and Health Effects, NIAAA. He joined NIA in 2011, responsible for the genetics and chromatin portfolio.

Research Interests/Portfolio


  • Genetics, epigenetics, and chromatin biology
  • DNA damage and genomic instability
  • Genetic and stochastic variations and aging heterogeneity
  • Human genetics of healthy aging
  • Genes and mechanisms controlling the rate of aging
  • Genomic and multi-omic approaches to study aging and longevity
  • Biology of telomere, retrotransposons, and other repetitive elements
  • RNA biology and metabolism (RNA editing, splicing, modification, noncoding RNAs)
  • Molecular aspects of progerias

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