Dr. Domenichiello earned his Ph.D. from the University of Toronto, working in the laboratory of Dr. Richard Bazinet where he studied brain fatty acid metabolism. In Dr. Bazinet’s lab, he conducted in vivo kinetic studies in awake animals, which required using a variety of analytical techniques (gas chromatography, high pressure liquid chromatography, ultra-high performance liquid chromatography and mass spectrometry) to measure synthesis rates and rates of uptake into the brain of polyunsaturated fatty acids. Additionally, Dr. Domenichiello examined the effects of dietary fatty acids on brain function, metabolism and biochemistry. Currently, Dr. Domenichiello is focused on studying the effects of oxidized lipid mediators on the nervous system with a particular focus on pain and Alzheimer’s disease. Specifically, he is using ultra high-performance liquid chromatography-tandem mass spectrometry to identify and measure novel oxidized lipid mediators in tissues and carrying out a variety of biochemical and rodent behavioral analyses to characterize the effects of oxidized lipid mediators in the body.