Dr. Croteau received her Ph.D. from Johns Hopkins University School of Medicine. She conducted post-doctoral studies at the Miller Institute UC Berkeley, Lineberger Cancer Center UNC, and NIEHS. She works on DNA repair, premature-aging disorders, and transcriptomics.
Dr. Croteau investigates how DNA repair deficiencies impact progression of Alzheimer’s disease (AD) in mouse and worm models. DNA repair modulates many cellular processes including chromatin, cell cycle, inflammation, and mitochondrial function. She is particularly interested in how gene expression changes contribute to phenotypic outcomes. She is using spatial transcriptomics to investigate AD pathology before and after drug treatment.
Dr. Croteau is also leading the Biomedical Data Science initiative which brings cutting edge training in data science to NIA staff. If you have any topics for training, feel free to email her.