Dr. Paul Barrett, joined the Division of Neuroscience as a Program Director in the Neurobiology of Aging and Neurodegeneration Branch in June. Dr. Barrett comes to the NIA from the Office of Strategic Coordination (The Common Fund) in the NIH Office of the Director where he was a health specialist since 2016. During this time Dr. Barrett conducted in-depth program evaluations, handled scientific communications, and helped develop new funding opportunities for multiple Common Fund programs.
Dr. Barrett received his Ph.D. in Biochemistry from Vanderbilt University and his thesis research focused on how the structural and cholesterol binding properties of the amyloid precursor protein impact Aβ generation in Alzheimer’s disease using techniques such as NMR spectroscopy and confocal microscopy. He was a postdoctoral fellow at the University of Pittsburgh where his research focused on how α-synuclein interacts with the mitochondrial protein import machinery and how these interactions can promote dopaminergic cell death in Parkinson’s disease in vitro, in the rodent brain, and in human tissue. Dr. Barrett is responsible for overseeing research on metabolism and cellular homeostasis in the aging brain.