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Leading The Charge: Expanding Collaborative, Cross-Disciplinary Research for the Prevention, Treatment, and Care of Dementia — Bypass Budget FY22

The FY 2022 NIH Professional Judgment Budget highlights a collaborative, cross-disciplinary research agenda and progress toward the national research goal of treating and preventing Alzheimer’s and related dementias by 2025. This is the sixth such annual budget proposal, which estimates the additional funding needed to reach the 2025 goal.


FY 2021 bypass budget report coverBypass Budget Proposal for Fiscal Year 2022 — Leading The Charge: Expanding Collaborative, Cross-Disciplinary Research for the Prevention, Treatment, and Care of Dementia — Bypass Budget FY22 (PDF, 5.37M)

Read the full professional judgment budget, which describes research directions and an estimate of the funds in FY 2022, above NIH’s estimated base budget, that would enable NIH to fully pursue that research.


executive summaryFiscal Year 2022 Executive Summary (PDF, 371K)

This executive summary outlines the toll Alzheimer’s takes on the United States and promising opportunities in Alzheimer’s and related dementias research that NIH is pursuing.


milestones databaseAD+ADRD Research Implementation Milestones Database

Users can browse the Alzheimer's and related dementias milestones by eight focus areas and further refine by more targeted research implementation areas.


As mandated in Section 230, Division G of the Consolidated and Further Continuing Appropriations Act of 2015, NIH will prepare and submit to the President, for review and transmittal to Congress, this annual professional judgment budget through 2025. Only two other areas of biomedical research — cancer and HIV/AIDS — have been the subject of such special budget development aimed at speeding discovery. This approach is often referred to as a “bypass budget” because of its direct transmission to the President and then to Congress without modification through the traditional Federal budget process.

NIH welcomes this opportunity to develop a budget for expanding on the robust research program for Alzheimer’s and related dementias. It is built on a rigorous, extensive planning process that gauged progress in research, assessed emerging and new scientific opportunities to build on that progress, and calculated the additional funds necessary to capitalize on those opportunities and move more quickly in the most promising directions.

For Bypass Budget Proposals from earlier years, access the Bypass Budget Proposal archive.

For a report of recent scientific progress against the milestones, access the Report of 2019-2020 Scientific Advances for the Prevention, Treatment, and Care of Dementia.