Symptoms

Falls may be sign of future Alzheimer’s disease, cognitive decline

Cognitively normal older adults with evidence of early brain changes typical of Alzheimer’s disease fell more often than did their peers without these brain changes, a new study reported online in Neurology. The results suggest that declines in mobility may precede the symptoms of cognitive decline found in Alzheimer’s disease.

Understanding Memory Loss

English

What’s the difference between mild forgetfulness and more serious memory problems? Find out about memory problems, including Alzheimer's disease and dementia, and how to get help for serious memory loss.

Understanding Alzheimer's Disease

English

This 19-page easy-to-read booklet describes what happens when someone has Alzheimer’s disease and how it differs from normal aging. Read about when to see the doctor, possible treatments, and how patients and caregivers can get help.

NIH-supported clinical trial finds antidepressant reduces Alzheimer’s agitation

NIH-funded researchers are testing interventions to alleviate psychiatric conditions and symptoms, such as agitation, that distress people with Alzheimer’s and their caregivers. The goal is to identify treatments that are safer and more effective than the currently available antipsychotic drugs that are linked to increased risk for stroke and excessive sedation. Agitation, a syndrome that includes anxious, disruptive, or aggressive behavior, is common in the later stages of dementia and often leads to placing a loved one in residential care.

The Dementias

English

Get an overview of dementia, including its many types, risk factors, diagnosis, treatment, and research in this publication from the National Institute of Neurological Disorders and Stroke and the National Institute on Aging, both part of the National Institutes of Health.

Latest NIH Alzheimer’s research progress report available

A new online report from the National Institutes of Health (NIH) highlights recent progress in NIH-supported Alzheimer’s disease research.

Prepared annually by the National Institute on Aging (NIA) at NIH, the latest report -- 2011-2012 Alzheimer’s Disease Progress Report: Intensifying the Research Effort -- describes new investments and summarizes research in several areas:

Managing Alzheimer's Disease Communication and Behavior Problems: A Resource List

Caregivers face a variety of challenges when a loved one develops Alzheimer’s disease or another dementia, including communicating with the memory-impaired person and responding to difficult behaviors. This resource list offers a selection of articles, books, videos, and other materials that may help.

Some resources on this list are free; others must be purchased. To buy an item, please contact the publisher to confirm price and payment information. Many items are also available from traditional and online bookstores.

Part 2: What Happens to the Brain in AD

English

The Hallmarks of AD

Alzheimer’s disease disrupts critical metabolic processes that keep neurons healthy. These disruptions cause nerve cells in the brain to stop working, lose connections with other nerve cells, and finally die. The destruction and death of nerve cells causes the memory failure, personality changes, problems in carrying out daily activities, and other features of the disease.

Alzheimer's Disease Fact Sheet

English

Explore the changes in the brain that cause Alzheimer’s, symptoms, disease stages, diagnosis, and treatment. Also includes advice for caregivers and a list of other resources.

Alzheimer's Disease: Unraveling the Mystery

English

An essential primer on Alzheimer’s disease, this 80-page publication describes how the brain works and how it changes with age in healthy people and people with Alzheimer’s. Research on causes, diagnosis, prevention, potential treatments, and caregiver support is summarized. Look for full-color illustrations, a glossary, and a list of resources.

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