Research and Funding

Measurements in the Health ABC Study

Appendix 1

Core Components of the Health ABC Clinic Examination and Interview by Study Year
Clinic Examination

Year 1

Year 2

Year 3

Year 4

Year 5

Year 6

Year 8&10

DEXA - whole body / hip

WB/H

WB

WB/H

WB

WB/H

WB

WB/H

Wt / ht / circumferences

X

wt

wt

wt/ht

wt

X

X

Physical performance

X

 

 

X

 

X

X

Exercise tolerance - LDCW

X

X

 

X

 

X

X

20-meter walks

X

X

X

X

X

X

X

Grip strength

X

X

 

X

 

X

X

Knee extensor strength

X

X

 

X

 

X

X

Blood pressure

X

X

X

X

X

X

X

ECG

X

 

 

X

 

 

 

Ankle-brachial blood pressure

X

 

 

X

 

 

 

Spirometry

X

 

 

 

X

 

 

Medication use

X

X

X

 

X

X

X

Joint evaluation

 

X

 

 

X

X

 

Cognitive function

 

 

 

 

 

 

 

3MS - Teng

X

 

X

 

X

 

X

Digit-Symbol Substitution

X

 

 

 

X

 

X

Blood / urine collection

X

X

B

B

 

B

X

OGTT

X

 

 

 

 

 

 

Fasting glucose/insulin

X

G

 

G

 

X

X

Cholesterol HDL/LDL/total

X

 

 

T

 

X

X

Triglycerides

X

 

 

 

 

X

X

Cytokines

X

 

 

 

 

 

 

HgA1c

X

 

 

X

 

 

 

Albumin / Creatinine

X

 

 

 

 

 

 

Blood Count

 

 

X

 

 

 

 

Interview

 

 

 

 

 

 

 

Physical function

X

X

X

X

X

X

X

Physical activity

X

X

X

X

X

X

X

Work / volunteer / caregiving

X

X

X

X

X

X

X

Social / intellectual activity

S

 

 

 

 

S/I

S/I

Social network

X

 

X

 

 

 

 

Wt hx / change / intensions

X

X

X

X

X

X

X

Appetite / diet

X

X

A

A

A

A

A

Smoking / ETOH

X

 

S

 

S

 

X

Sleep habits

X

 

X

 

X

 

X

Fatigue symptoms

 

 

 

 

X

X

X

Apathy

 

 

 

 

 

X

X

Depressive symptoms

X

X

X

X

X

X

X

Anxiety symptoms

X

 

X

 

X

X

X

Control beliefs / mastery

X

X

X

X

X

X

X

Dx medical conditions / sx

X

X

X

X

X

X

X

Eyesight

X

 

X

 

 

X

X

Finances / income / insurance

X

 

 

 

X

 

 

Disease & Death Adjudication

X

X

X

X

X

X

X

Appendix 2

Special Features - Measures and Substudies in Health ABC in Years 1 through 6

Additional Clinic Measures

Year 1

Year 2

Year 3

Year 4

Year 5

Year 6

Funding Source

Thigh and Abdominal CT

X

 

 

 

 

X

NIDDK/NIA

Arterial Pulse Wave Velocity

X

         

NIA contract

Dental/Peridontal Exam

 

X

X

     

NIA contract

Knee x-ray / MRI

 

X

 X

X

X

X

NIA/NIAMS

Vision

   

X

     

NIA contract

Acuity

             

Contrast sensitivity

             

Depth perception

             

Olfaction

 

 

X

 

 

 

NIA contract

Ultrasound of the heel

 

X

 

 

X

 

NIA contract

Literacy

   

X

 

 

 

NIA contract

Arterial Venous Blood Gas

   

X

 

   

NIA contract

Isometric knee strength

 

 

X

 

X

 

NIA contract

Knee extensor muscle fatigue

 

 

X

 

 

 

NIA contract

Audiometric Testing

 

 

 

 

X

 

NIA contract

Ankle Strength

 

 

 

X

 

 

NIA contract

Executive Control Function

 

 

X

 

X

 

NIA contract

Peripheral Neuropathy

 

 

 

X

 

 

NIA contract

Monofilament

 

 

 

 

 

 

 

Peroneal nerve conduction

 

 

 

 

 

 

 

Vibration perception

 

 

 

 

 

 

 

Sit and Reach Flexibility

 

 

 

 

 

X

NIA contract

Substudies

 

 

 

 

 

 

 

Energy Expenditure

 

X

X

     

NIDDK

Doubly-labeled water

 

 

 

 

 

 

 

Resting metabolic rate

 

 

 

 

 

 

 

Bereavement

X

X

X

X

X

X

NIA contract

Cognitive Vitality

   

X

 

X

Year 7

NIA contract

Selective Reminding Test

 

 

 

 

 

   

Salthouse battery

 

 

 

 

 

 

 

Personality

             

Social / Intellectual activity

             

Weight Change

   

X

X

 

 

NIA contract

Descriptions of the clinical examinations, measurements and substudies can be found on the Health ABC web page.