Transgenic mice universally expressing the green fluorescent protein (GFP) under the human ubiquitin C (UBC) promoter (C57BL/6-tg(UBC-GFP)30Scha) were developed by Dr. Brian Schaeffer, and the breeding stock was generously provided by Dr. Philippa Marrack at National Jewish Medical and Research Center, Denver CO. The transgene is inbred on the C57BL/6 background. The mice are homozygous for the transgene, and there are no special husbandry concerns with these mice. Cells from these mice are used in cell transplantation studies.
Schaefer BC, Schaefer ML, Kappler JW, Marrack P, Kedl RM. Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol. 2001 Dec 15;214(2):110-22.