NIA's SBIR and Small Business Technology Transfer (STTR) programs support small businesses and nonprofit research organizations that conduct research leading to the development of products and services that improve the health and well-being of older Americans.
The goal is to translate research on aging, aging-related medical conditions and diseases, and special problems and needs of older Americans into innovative programs, systems, networks, and other products or services needed by health-care professionals, informal caregivers, and older Americans to maintain and/or improve their health, and to maintain and/or improve their overall sense of well-being.
All applicants are expected to develop, implement, and test the efficacy of their products and services. The SBIR-STTR programs target early-stage research and research development and encompass a broad range of research topics (see 2012 NIH SBIR-STTR Program Description and Research Topics  (PDF, 1.5M)) and types of research/research development, including preclinical translational research/research development and secondary research/research development.
Michael-David A.R.R. Kerns, M.B.A., M.S., Ph.D.
National Institutes of Health: National Institute on Aging
Email: firstname.lastname@example.org 
- Small Business Innovation Research-Small Business Technology Transfer (SBIR-STTR) Policy 
- What Is Expected of Applicants 
- Toolbox for Applicants 
- FAQs 
- The SBIR-STTR Programs were reauthorized in 2011: The Small Business Administration (SBA) has released interim guidance for all agencies who manage SBIR and STTR programs in light of the recent re-authorization P.L. 112-81. The guidance can be found in this blog  by Sean Greene at SBA. Please read the blog carefully. It discusses the timeline for implementation of the provisions in the re-authorization and when public comment will be solicited on the proposed regulations and policy directives. Per this guidance, in FY2012, NIH will raise the set asides to 2.6% for SBIR and .35% for STTR (they were 2.5% and 0.3% formerly). For all the other provisions in the re-authorization however, NIH will continue to work within the existing regulations and policy directive, until those regulations are amended and the policy directive is updated. This means business as usual for now. The full link for the guidance is here: http://sbir.gov/news/implementing-sbir-and-sttr-reauthorization-our-plan-attack .
- Changes coming to the Central Contractor Registry (CCR): CCR account requests and renewal services are changing. At the end of July 2012, CCR services are moving to the new System for Award Management  (SAM). The transition to the new system may delay your request for a CCR account. Please visit https://sam.gov  and the Grants.gov blog page  for details and additional information. We urge you begin the registration process NOW as all required registrations must be complete for a successful submission of an NIH grant application.
SBIR-STTR Program Descriptions & Research Topics:
- 2012 NIA SBIR-STTR Program Descriptions & Research Topics  (PDF, 1.5M)
- 2012 NIH SBIR Omnibus Solicitation for Small Business Innovation Research Grant Applications (SBIR [R43-R44]) 
- Lab to Marketplace: Tools for Brain and Behavioral Research (SBIR [R43-R44]) 
- 2012 NIH STTR Omnibus Solicitation for Small Business Technology Transfer Research Grant Applications (STTR [R41-R42])