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Phone: 301-496-1752
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  • SIRT1 repairs DNA but leads to age-related gene expression in mice
    May 12, 2009

    Scientists have found a mechanism involving the protein SIRT1 that links DNA damage with age-related changes in gene expression. The study in mice has striking parallels with findings from studies of a similar mechanism in yeast. Past...

  • Smallpox vaccine confers longtime immunity
    May 12, 2009

    The threat of smallpox resulting from bioterrorism has prompted a reassessment of the current population’s level of immunity. A recent study by researchers in the NIA’s Intramural Research Program shows that older adults who...

  • Bone remodeling protein works indirectly through gut
    May 12, 2009

    The protein Lrp5, long known to play a critical role in bone remodeling, appears to exert its effects through the gut, not directly through the bone, as previously thought, according to preclinical research published in Cell. The findings...

  • Hormone therapy linked to brain shrinkage
    May 12, 2009

    Two recent imaging studies shed light on how menopausal hormone therapy (MHT) may affect the brains of older women. Previous studies showed that MHT increased the likelihood that older women would have difficulty with thinking skills and...

  • PET scans with PiB show beta-amyloid in brains of cognitively normal older adults
    May 12, 2009

    Two recent NIA-funded studies used novel imaging techniques to explore the possible connection between the buildup of beta-amyloid protein deposits in the brains in living people and the risk of developing Alzheimer’s disease (AD)....

  • Meniscal tears common in older adults, even without symptoms
    May 12, 2009

    The prevalence of meniscal tears in adults increases with age, but often they are not accompanied by knee pain or other symptoms, according to a recent study supported in part by the NIA. Researchers led by Dr. Martin Englund of the Boston...

  • Research shows that happiness spreads through social groups
    May 12, 2009

    NIA-funded researchers have found that happiness is not an isolated phenomenon, unique to an individual, but rather spreads through social networks. Using data from the Framingham Heart Study, Drs. Nicholas Christakis of Harvard Medical...

  • Study shows metabolic adaptation in calorie restriction
    May 12, 2009

    Researchers at the Pennington Biomedical Research Center in Baton Rouge, LA, have shown that when people significantly reduce their calorie intake, they undergo a metabolic adaptation that results in a slower metabolic rate. The slower...

  • cover of exercise guide
    Exercise for all older adults: NIA guide shows and tells
    May 1, 2009

    The NIA’s new exercise guide for older adults has something for everyone. Whether healthy, chronically ill, or disabled, most older people can be physically active. The newly updated guide shows them how. “A central goal of...

  • Researcher using computer in lab
    New drugs for Alzheimer's: NIA boosts translational research
    May 1, 2009

    Dr. Roberta Diaz Brinton of the University of Southern California (USC) in Los Angeles knew she needed to take the next step. Her studies showed that allopregnanolone, one of the most common steroids in the brain, boosted the brain...

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