Alzheimer's Disease Education and Referral Center

Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI)

Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI)

Overall Status: 
Recruiting
Brief Description: 

Dementia is considered to be present when a person can no longer handle complex activities of daily living, such as managing finances. This study will investigate the relationship between changes in the ability to handle finances and brain perfusion (blood flow in the brain), as measured by arterial spin-labeling MRI. Subjects will also undergo neuropsychological tests focusing on several types of memory and thought processes, with special emphasis on semantic memory. The study will examine whether changes in financial capacity are better predicted by neuropsychological tests or the brain scan.

Patient Qualifications: 
Min AgeMax AgeGenderHealthy Volunteers
50 Years
89 Years
Both
Accepts Healthy Volunteers
Inclusion Criteria: 

  • Normal cognition or memory impairment (MCI or mild Alzheimer's disease)
  • English speaking
  • Right handed
  • Adequate vision and hearing to take part in tests
  • Able and willing to undergo MRI scan
  • Medically and psychiatrically stable

Exclusion Criteria: 

  • Brain disease (such as tumor, Parkinson's disease, major stroke)
  • Pregnancy
  • Inability to tolerate MRI (due to metal in body or claustrophobia)

Detailed Description: 

None provided.

Locations: 
Map Marker CityStateZip CodeStatusPrimary Contact

Geolocation is 33.5065561, -86.8044586

Site
Birmingham
Alabama
35233
Recruiting
Name: David G Clark, MD
Phone: 205-996-6050
Email: dgclark@uab.edu
Lead Sponsor: 
Agency
Department of Veterans Affairs
Collaborator Sponsor: 
Agency
University of Alabama at Birmingham
Facility Investigators: 
NameRoleAffiliation
David G. Clark, MD
Principal Investigator
VA Medical Center, Birmingham
Study Contact: 
NamePhonePhone ExtEmail
David G. Clark, MD
205-996-6050
Kathryn L. Burgio, PhD
205-933-8101
x 7307
Locations
 
 
ClinicalTrials.gov ID 
NCT00880555 (follow link to view full record on ct.gov in new window)
Official Title: 
Semantic Memory, Financial Capacity and Brain Perfusion in MCI
Study Start Date: 
April 2009
Study End Date: 
December 2014
Disease Stage: 
Pre-clinical
Early
Enrollment: 
160