Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI)
Semantic Memory, Financial Capacity, and Brain Perfusion in Mild Cognitive Impairment (MCI)
Overall Status:
Recruiting
Brief Description:
Dementia is considered to be present when a person can no longer handle complex activities of daily living, such as managing finances. This study will investigate the relationship between changes in the ability to handle finances and brain perfusion (blood flow in the brain), as measured by arterial spin-labeling MRI. Subjects will also undergo neuropsychological tests focusing on several types of memory and thought processes, with special emphasis on semantic memory. The study will examine whether changes in financial capacity are better predicted by neuropsychological tests or the brain scan.
Patient Qualifications:
| Min Age | Max Age | Gender | Healthy Volunteers |
|---|---|---|---|
50 Years | 89 Years | Both | Accepts Healthy Volunteers |
Inclusion Criteria:
- Normal cognition or memory impairment (MCI or mild Alzheimer's disease)
- English speaking
- Right handed
- Adequate vision and hearing to take part in tests
- Able and willing to undergo MRI scan
- Medically and psychiatrically stable
Exclusion Criteria:
- Brain disease (such as tumor, Parkinson's disease, major stroke)
- Pregnancy
- Inability to tolerate MRI (due to metal in body or claustrophobia)
Detailed Description:
None provided.
Locations:
| Map Marker | City | State | Zip Code | Status | Primary Contact | |
|---|---|---|---|---|---|---|
Geolocation is 33.5065561, -86.8044586 | VA Medical Center | Birmingham | Alabama | 35233 | Recruiting |
Lead Sponsor:
| Agency |
|---|
Department of Veterans Affairs |
Collaborator Sponsor:
| Agency |
|---|
University of Alabama at Birmingham |
Facility Investigators:
| Name | Role | Affiliation |
|---|---|---|
David G. Clark, MD | Principal Investigator | VA Medical Center, Birmingham |
Study Contact:
| Name | Phone | Phone Ext | |
|---|---|---|---|
David G. Clark, MD | 205-996-6050 | ||
Kathryn L. Burgio, PhD | 205-933-8101 | x 7307 |
Locations
ClinicalTrials.gov ID
NCT00880555 (follow link to view full record on ct.gov in new window)
Official Title:
Semantic Memory, Financial Capacity and Brain Perfusion in MCI
Study Start Date:
April 2009
Study End Date:
December 2014
Disease Stage:
Pre-clinical
Early
Enrollment:
160
