Alzheimer's Disease Education and Referral Center

Search for Clinical Trials

Your Search for state of Pennsylvania Identified 13 Trial(s):

  • 1. ADvance Deep Brain Stimulation in Patients with Mild Probable Alzheimer's Disease

    Purpose: To evaluate the safety of deep brain stimulation of the fornix (DBS-f) in people with mild Alzheimer's disease.

  • 2. Arterial Spin Labeling (ASL) MRI for Cognitive Decline

    Purpose: To determine the value of arterial spin labeling magnetic resonance imaging, a measure of blood flow to the brain, in finding the cause of cognitive decline in people with mild cognitive impairment.

  • 3. Aspirin in Reducing Events in the Elderly (ASPREE)

    Purpose: To examine whether the potential benefits of low-dose aspirin outweigh the risks in people over age 70.

  • 4. BAN2401 for Early Alzheimer's Disease

    Purpose: To determine the effectiveness of the experimental drug BAN2401 as a possible treatment for people with mild cognitive impairment or mild Alzheimer's disease.

  • 5. Clinical Evaluation of Florbetapir F 18 (18F-AV-45)

    Purpose: To standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden.

  • 6. Dominantly Inherited Alzheimer Network (DIAN)

    Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.

  • 7. Mild Cognitive Impairment and Obstructive Sleep Apnea (MEMORIES)

    Purpose: To determine the study design and methods for a full-scale clinical trial that will determine whether treatment of obstructive sleep apnea in older adults with mild cognitive impairment delays cognitive decline and preserves everyday function.

  • 8. MK-8931 for Mild to Moderate Alzheimer's Disease

    Purpose: To assess the efficacy and safety of MK-8931 as a possible treatment for Alzheimer's disease.

  • 9. Preventing Cognitive Decline in African Americans with Mild Cognitive Impairment

    Purpose: To determine whether increasing participation in cognitive, physical, and/or social activities prevents cognitive decline in older African Americans with mild cognitive impairment (MCI).

  • 10. Retaining Cognition While Avoiding Late-Life Depression (RECALL)

    Problem: To test Problem Solving Therapy as a way to prevent major depression in people with mild cognitive impairment.

  • 11. RO4602522 in Patients with Moderate Alzheimer Disease on Donepezil or Rivastigmine Therapy

    Purpose: To evaluate the efficacy and safety of RO4602522 in people with moderate-stage Alzheimer disease who take donepezil or rivastigmine.

  • 12. Systolic Blood Pressure Intervention Trial: Memory and Cognition in Decreased Hypertension (SPRINT-MIND)

    Purpose: To determine whether intensive blood pressure lowering will reduce the incidence of all-cause dementia, reduce the decline of global cognitive function in key specific domains, and show changes in brain structure.

  • 13. TRx0237 for Mild to Moderate Alzheimer's Disease

    Purpose: To determine the safety and efficacy of the experimental drug TRx0237 to treat people with mild to moderate Alzheimer's disease.

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