Alzheimer's Disease Education and Referral Center

Search for Clinical Trials

Your Search for state of New York Identified 25 Trial(s):

  • 1. AC-1204 for Mild to Moderate Alzheimer's Disease

    Purpose: To evaluate the effects of AC-1204 on cognition, activities of daily living, quality of life, pharmacokinetic measures, and safety in people with mild to moderate Alzheimer's disease.

  • 2. Aspirin in Reducing Events in the Elderly (ASPREE)

    Purpose: To examine whether the potential benefits of low-dose aspirin outweigh the risks in people over age 70.

  • 3. AVP-923 for Treatment of Agitation in Alzheimer's Patients

    Purpose: To evaluate the safety, tolerability, and efficacy of AVP-923 (dxtromethorphan/qinidine) for the treatment of agitation in people with Alzheimer's disease.

  • 4. BAN2401 for Early Alzheimer's Disease

    Purpose: To determine the effectiveness of the experimental drug BAN2401 as a possible treatment for people with mild cognitive impairment or mild Alzheimer's disease.

  • 5. BIIB037 in Prodromal or Mild Alzheimer's Disease

    Purpose: To evaluate the safety and tolerability of BIIB037 in people with prodromal or mild Alzheimer's disease.

  • 6. Brain Alterations and Cognitive Impairment in Older Adults with Heart Failure

    Purpose: To study the relationship between brain MRI results and cognitive impairment in older adults with heart failure.

  • 7. Cognitive Benefits of Aerobic Exercise Across the Age Span

    Purpose: To test the hypothesis that aerobic exercise leads to improved cognitive function.

  • 8. Combination Treatment Study for Memory Impairment and Depression

    Purpose: To determine the response of older adults with both depression and cognitive impairment to donepezil vs. placebo after treatment with antidepressants. The goal is improve cognition and delay conversion to dementia.

  • 9. Dominantly Inherited Alzheimer Network (DIAN)

    Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.

  • 10. ELND005 for Agitation and Aggression in Alzheimer's Disease

    Purpose: To determine whether ELND005 is effective in treating symptoms of agitation and aggression in people with Alzheimer's disease.

  • 11. Exercise, Age-Related Memory Decline, and Hippocampal Function

    Purpose: To test the hypothesis that aerobic exercise leads to increased blood volume in the brain, specifically in the dentate gyrus of the hippocampus.

  • 12. Gantenerumab for Prodromal Alzheimer's Disease

    Purpose: To evaluate the safety and efficacy of the experimental drug gantenerumab on cognition and functioning in people with prodromal (very early stage) Alzheimer's disease.

  • 13. Home-Delivered Intervention for Depressed, Cognitively Impaired Elders

    Purpose: To test the efficacy of Problem Adaptation Therapy (PATH), a home-delivered psychosocial intervention for elders with major depression, memory problems, and disability.

  • 14. Imaging of Cognition, Learning, and Memory in Aging

    Purpose: To study how the brain functions when it performs explicit memory tasks and how this changes as a function of aging.

  • 15. Living with Frontotemporal Dementia

    Purpose: To better understand the experience of people with frontotemporal dementia and their caregivers in order to develop better therapies.

  • 16. Metabolic Cerebral Imaging in Incipient Dementia (MCI-ID)

    Purpose: To determine whether positron emission tomography (PET) scanning can help distinguish patients with early Alzheimer's changes in their brains from those having other causes of cognitive impairment more accurately than current clinical practices.

  • 17. MK-8931 for Mild to Moderate Alzheimer's Disease

    Purpose: To assess the efficacy and safety of MK-8931 as a possible treatment for Alzheimer's disease.

  • 18. Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil

    Purpose: To determine if difficulty with the sense of smell can predict conversion from mild cognitive impairment to Alzheimer's disease and track response to donepezil therapy.

  • 19. PET Imaging Agent [18F]AZD4694 in Probable Alzheimer's Disease

    Purpose: To assess the safety and efficacy of the imaging agent [18F]AZD4694 in positron emission tomography (PET) in people with probable Alzheimer's disease.

  • 20. PF-05212377 for People with Alzheimer's Disease and Neuropsychiatric Symptoms

    Purpose: To evaluate safety and efficacy of the experimental drug PF-05212377 in people with mild to moderate Alzheimer's disease and neuropsychiatric symptoms who take donepezil.

  • 21. Riluzole for Mild Alzheimer's Disease

    Purpose: To test the safety and effectiveness of the drug riluzole for treating mild Alzheimer's disease.

  • 22. RO4602522 in Patients with Moderate Alzheimer Disease on Donepezil or Rivastigmine Therapy

    Purpose: To evaluate the efficacy and safety of RO4602522 in people with moderate-stage Alzheimer disease who take donepezil or rivastigmine.

  • 23. Systolic Blood Pressure Intervention Trial: Memory and Cognition in Decreased Hypertension (SPRINT-MIND)

    Purpose: To determine whether intensive blood pressure lowering will reduce the incidence of all-cause dementia, reduce the decline of global cognitive function in key specific domains, and show changes in brain structure.

  • 24. TRx0237 for Mild Alzheimer's Disease

    Purpose: To determine the safety and efficacy of the experimental drug TRx0237 to treat people with mild Alzheimer's disease.

  • 25. TRx0237 for Mild to Moderate Alzheimer's Disease

    Purpose: To determine the safety and efficacy of the experimental drug TRx0237 to treat people with mild to moderate Alzheimer's disease.

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