Purpose: To evaluate the safety and tolerability of BIIB037 in people with prodromal or mild Alzheimer's disease.
Purpose: To standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden.
Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Purpose: To assess the safety, tolerability, and biomarker efficacy of gantenerumab and solanezumab in individuals who have a genetic mutation for autosomal-dominant Alzheimer's disease.
Purpose: To assess the efficacy and safety of MK-8931 as a possible treatment for Alzheimer's disease.
Purpose: To evaluate the efficacy and safety of RO4602522 in people with moderate-stage Alzheimer disease who take donepezil or rivastigmine.
Purpose: To determine whether intensive blood pressure lowering will reduce the incidence of all-cause dementia, reduce the decline of global cognitive function in key specific domains, and show changes in brain structure.