Purpose: To evaluate the effects of AC-1204 on cognition, activities of daily living, quality of life, pharmacokinetic measures, and safety in people with mild to moderate Alzheimer's disease.
Purpose: To determine the effectiveness of the experimental drug BAN2401 as a possible treatment for people with mild cognitive impairment or mild Alzheimer's disease.
Purpose: To standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden.
Purpose: To identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Purpose: To determine whether positron emission tomography (PET) scanning can help distinguish patients with early Alzheimer's changes in their brains from those having other causes of cognitive impairment more accurately than current clinical practices.
Purpose: To track changes over time among individuals with frontotemporal dementia (FTD) in the brain using imaging and other biomarkers and to compare the utility of different kinds of images.
Purpose: To determine whether intensive blood pressure lowering will reduce the incidence of all-cause dementia, reduce the decline of global cognitive function in key specific domains, and show changes in brain structure.
Purpose: To determine the safety and efficacy of the experimental drug TRx0237 to treat people with mild Alzheimer's disease.
Purpose: To determine the safety and efficacy of the experimental drug TRx0237 to treat people with mild to moderate Alzheimer's disease.