Purpose: To evaluate the effects of AC-1204 on cognition, activities of daily living, quality of life, pharmacokinetic measures, and safety in people with mild to moderate Alzheimer's disease.
Purpose: To evaluate the safety of deep brain stimulation of the fornix (DBS-f) in people with mild Alzheimer's disease.
Purpose: To determine the effectiveness of the experimental drug BAN2401 as a possible treatment for people with mild cognitive impairment or mild Alzheimer's disease.
Purpose: To evaluate the safety and tolerability of BIIB037 in people with prodromal or mild Alzheimer's disease.
Purpose: To standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden.
Purpose: To determine whether positron emission tomography (PET) scanning can help distinguish patients with early Alzheimer's changes in their brains from those having other causes of cognitive impairment more accurately than current clinical practices.
Purpose: To assess the efficacy and safety of MK-8931 as a possible treatment for Alzheimer's disease.
Purpose: To test the safety and effectiveness of the drug Nuedexta (dextromethorphan/quinidine) as a treatment for pseudobulbar affect in people with Alzheimer's disease.
Purpose: To assess the safety and tolerability of RG1662 in individuals with Down syndrome.
Purpose: To determine whether intensive blood pressure lowering will reduce the incidence of all-cause dementia, reduce the decline of global cognitive function in key specific domains, and show changes in brain structure.
Purpose: To determine the safety and efficacy of the experimental drug TRx0237 to treat people with mild Alzheimer's disease.