PhytoSERMs for Menopause Symptoms and Age-Associated Memory Decline
PhytoSERMs for Menopause Symptoms and Age-Associated Memory Decline
Overall Status:
Recruiting
Brief Description:
The purpose of this study is to evaluate the safety and efficacy of a soy-based dietary supplement, phytoSERM (selective estrogen receptor modulator), for hot flashes and age-associated memory loss. PhytoSERMs are plant-derived substances that possess SERM qualities, similar to synthetically manufactured drugs of the same category.
Patient Qualifications:
| Min Age | Max Age | Gender | Healthy Volunteers |
|---|---|---|---|
48 Years | 58 Years | Female | No |
Inclusion Criteria:
- Postmenopausal
- Vasomotor symptom(s) such as hot flashes
- Memory complaint
Exclusion Criteria:
- History of clinically significant stroke
- Current evidence or history in past 2 years of epilepsy, seizure, focal brain lesion, head injury with loss of consciousness, or major psychiatric disorder, including psychosis, major depression, bipolar disorder, alcohol or substance abuse
- Known allergy to soy-derived products
- Hypersensitivity to estrogens or progestins
Detailed Description:
None provided.
Locations:
| Map Marker | City | State | Zip Code | Status | Primary Contact | |
|---|---|---|---|---|---|---|
Geolocation is 34.0502898, -118.2117257 | University of Southern California Keck School of Medicine | Los Angeles | California | 90033 | Recruiting |
Lead Sponsor:
| Agency |
|---|
University of Southern California |
Collaborator Sponsor:
| Agency |
|---|
National Institute on Aging |
Facility Investigators:
| Name | Role | Affiliation |
|---|---|---|
Lon S. Schneider, MD | Principal Investigator | University of Southern California |
Study Contact:
| Name | Phone | |
|---|---|---|
Gerson Hernandez, MD | 323-442-5775 | |
Nadine Diaz | 323-442-5775 |
Locations
ClinicalTrials.gov ID
NCT01723917 (follow link to view full record on ct.gov in new window)
Official Title:
Estrogen Receptor-beta phytoSERMs for Management of Menopause and Age-Associated Memory Decline
Study Start Date:
July 2012
Study End Date:
September 2013
Disease Stage:
Early
Enrollment:
78
