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Find more clinical trials

Influence of Fitness on Brain and Cognition

Start: April 2006
End: May 2012
Enrollment: 140

What Is This Study About?

The purpose of this study is to examine the effect of aerobic fitness training on older adults' human cognition, brain structure, and brain function.

Do I Qualify To Participate in This Study?

Minimum Age: 60 Years

Maximum Age: 75 Years

Must have:

  • For sedentary older adults, no physical activity during the last 6 months; for young comparison sample, moderately active lifestyle and ability to perform exercise
  • Personal physician's examination and consent to participate in testing and exercise or control intervention
  • Successful completion of graded exercise test without evidence of cardiac abnormalities or responses
  • Adequate performance on the Pfeiffer (1979) Mental Status measure
  • Corrected (near and far) vision of 20/40 or better
  • Right-handedness
  • Intention to remain in the local area during the study period

Must NOT have:

  • For sedentary older adults, physical activity on regular basis (twice or more per week) during the last 6 months; for young comparison sample, sedentary or highly active/athletic lifestyle
  • Any physical disability that prohibits mobility (walking), stretching, and other movement
  • Geriatric Depression Scale score indicative of clinical depression
  • Presence of implanted device such as cardiac pacemaker or autodefibrillator; neural pacemaker, aneurysm clip in the central nervous system (CNS); cochlear implants; metallic bodies in the eye or CNS; any form of wires or metal devices that concentrate radiofrequency fields
  • Left-handedness
  • Individuals with chronic inflammation (for example, severe arthritis, psoriasis, inflammatory bowel disease, asthma, polyneuropathies, lupus)
  • Intent to move or take a vacation longer than 1 month during the study period

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: University of Illinois at Urbana-Champaign

Collaborator Sponsor

  • National Institute on Aging (NIA)

Source: ClinicalTrials.gov ID: NCT00438347

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An official website of the U.S. government, managed by the National Institute on Aging at the National Institutes of Health