Start:
January 2014
End:
January 2017
Enrollment:
110
What Is This Study About?
This study will determine whether an aerobic exercise program will alter markers of immune cell aging, improve blood pressure, and decrease psychological distress in caregivers of people with Alzheimer's disease. Results will be compared with those for a control group of caregivers who do not exercise.
Do I Qualify To Participate in This Study?
Must have:
- Women must be postmenopausal
- Body Mass Index (BMI) below 40
- Family member providing at least 10 hours per week of unpaid care for an adult relative with Alzheimer's disease or another dementia for more than 6 months since diagnosis
- Perceived stress
- Do not meet federal recommendations for exercise (150 minutes per week of moderate activity or 75 minutes of vigorous activity)
Must NOT have:
- Major chronic disease or major injury that interferes with activity levels, as advised by a medical practitioner (including autoimmune disorders; severe asthma; emphysema or chronic bronchitis; history of stroke, heart attack, cardiovascular disease, epilepsy, or brain injury)
- Heart attack or repeated chest pain, pressure, and/or arrhythmia in the past 6 months
- Cancer that is not in remission; chemotherapy or radiation within the past 5 years
- Eating disorders
- Current substance abuse/dependence that may interfere with ability to exercise
- Current post-traumatic stress disorder
- Current or recent smoker (within the past 5 years)
- Prohibited medications: oral steroids; prescription or other drugs that might interfere with outcome measures
- Any physical impairment that prevents participation in moderate level of physical activity (for example, musculoskeletal problems or prosthesis)
- Inability to walk a block or climb stairs without chest pain, losing breath, or dizziness
Need Help?
Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at
800-438-4380
or
email ADEAR.
Where Is This Study Located?
Source:
ClinicalTrials.gov ID:
NCT01993082