Effects of Mental Stimulation in Patients with Mild Cognitive Impairment
Effects of Mental Stimulation in Patients with Mild Cognitive Impairment
Overall Status:
Recruiting
Brief Description:
The purpose of this study is to learn if mentally stimulating activities can improve memory and other types of thinking in patients with mild cognitive impairment. The study will compare the effects of different methods of mental stimulation.
Patient Qualifications:
| Min Age | Max Age | Gender | Healthy Volunteers |
|---|---|---|---|
50 Years | N/A | Both | No |
Inclusion Criteria:
- 55 years of age or older
- Meet criteria for amnestic mild cognitive impairment (MCI)
- Capacity to give informed consent
Exclusion Criteria:
- History of drug or alcohol dependence
- Severe psychiatric conditions associated with psychosis (e.g., schizophrenia)
- Recent stroke
- Clinical diagnosis of probable Alzheimer's disease
- History of seizure disorder, serious head trauma, or other medical, psychiatric, or neurological conditions associated with significant cognitive impairment (e.g., Parkinson's disease, Korsakoff's, HIV)
- Prohibited medications: Alzheimer's disease medications (e.g., cholinesterase inhibitors, memantine)
Detailed Description:
This Phase II study will compare the effects of different methods of mental stimulation. The intervention involves six classroom-style educational sessions and 10 mental stimulation studies involving computerized memory tasks.
Locations:
| Map Marker | City | State | Zip Code | Status | Primary Contact | |
|---|---|---|---|---|---|---|
Geolocation is 0, 0 | Johns Hopkins Bayview Medical Center | Baltimore | Maryland | 21224 | Recruiting |
Lead Sponsor:
| Agency |
|---|
Johns Hopkins University |
Collaborator Sponsor:
| Agency |
|---|
National Institute on Aging (NIA) |
Facility Investigators:
| Name | Role | Affiliation |
|---|---|---|
Miriam Mintzer, PhD | Principal Investigator | Johns Hopkins University |
Study Contact:
| Name | Phone | |
|---|---|---|
Crystal L. Barnhouser | 410-550-2688 |
Locations
ClinicalTrials.gov ID
NCT01212692 (follow link to view full record on ct.gov in new window)
Official Title:
A Theoretically Based Memory Training Intervention in Mild Cognitive Impairment
Study Start Date:
October 2010
Study End Date:
June 2013
Disease Stage:
Early
Enrollment:
72
