Alzheimer's Disease Education and Referral Center

Effects of Mental Stimulation in Patients with Mild Cognitive Impairment

Effects of Mental Stimulation in Patients with Mild Cognitive Impairment

Overall Status: 
Active, not recruiting
Brief Description: 

The purpose of this study is to learn if mentally stimulating activities can improve memory and other types of thinking in patients with mild cognitive impairment. The study will compare the effects of different methods of mental stimulation.

Patient Qualifications: 
Min AgeMax AgeGenderHealthy Volunteers
50 Years
N/A
Both
No
Inclusion Criteria: 

  • 55 years of age or older
  • Meet criteria for amnestic mild cognitive impairment (MCI)
  • Capacity to give informed consent

Exclusion Criteria: 

  • History of drug or alcohol dependence
  • Severe psychiatric conditions associated with psychosis (e.g., schizophrenia)
  • Recent stroke
  • Clinical diagnosis of probable Alzheimer's disease
  • History of seizure disorder, serious head trauma, or other medical, psychiatric, or neurological conditions associated with significant cognitive impairment (e.g., Parkinson's disease, Korsakoff's, HIV)
  • Prohibited medications: Alzheimer's disease medications (e.g., cholinesterase inhibitors, memantine)

Detailed Description: 
This Phase II study will compare the effects of different methods of mental stimulation. The intervention involves six classroom-style educational sessions and 10 mental stimulation studies involving computerized memory tasks.
Locations: 
Map Marker CityStateZip CodeStatusPrimary Contact

Geolocation is 39.2713976, -76.5603828

BPRU, Johns Hopkins Bayview Medical Center
Baltimore
Maryland
21224
Name:
Phone:
Lead Sponsor: 
Agency
Johns Hopkins University
Collaborator Sponsor: 
Agency
National Institute on Aging (NIA)
Facility Investigators: 
NameRoleAffiliation
Miriam Mintzer, PhD
Principal Investigator
Johns Hopkins University
Study Contact: 
NamePhoneEmail
Crystal L. Barnhouser
410-550-2688
Locations
 
 
ClinicalTrials.gov ID 
Official Title: 
A Theoretically Based Memory Training Intervention in Mild Cognitive Impairment
Study Start Date: 
October 2010
Study End Date: 
June 2014
Disease Stage: 
Early
Enrollment: 
72