Alzheimer's Disease Education and Referral Center

Effect of Blueberries on Cognition and Body Composition in Elderly with Mild Cognitive Decline

Effect of Blueberries on Cognition and Body Composition in Elderly with Mild Cognitive Decline

Overall Status: 
Recruiting
Brief Description: 

This study will examine the effect of blueberry consumption on cognitive decline and body composition in older adults with mild cognitive decline. The investigators hypothesize that participants who consume blueberries will experience an improvement in cognitive abilities, as measured by a standardized battery of tests, compared with those who consume a placebo. They may also show an increase in processing speed, an improvement in memory abilities, an improvement in body composition, and a decrease in oxidative stress and inflammation.

Patient Qualifications: 
Min AgeMax AgeGenderHealthy Volunteers
65 Years
79 Years
Both
Accepts Healthy Volunteers
Inclusion Criteria: 
    • Body Mass Index between 18.5 and 34.5
    • Family member, friend, or other individual who can report on participant's memory decline
Exclusion Criteria: 
    • History of central nervous system or psychiatric disorders
    • Diagnosis of dementia or Alzheimer's disease
    • Diabetes
    • Smoking more than 20 cigarettes per day
    • Gastrointestinal/digestive disorders
    • Uncontrolled chronic disease
Detailed Description: 

In this Phase II study, participants will consume a dietary supplement containing 35 grams of freeze-dried blueberries or a placebo daily for 6 months to test the intervention's effect on cognition, as measured by tests of cognitive performance; body mass composition (fat mass vs. lean mass); and oxidative stress and inflammatory markers, as measured in blood and urine.

Locations: 
Map Marker CityStateZip CodeStatusPrimary Contact

Geolocation is 35.4989016, -80.6659842

Site
Kannapolis
North Carolina
28081
Recruiting
Name:
Phone:
Lead Sponsor: 
Agency
University of North Carolina, Chapel Hill
Collaborator Sponsor: 
Facility Investigators: 
NameRoleAffiliation
Carol L. Cheatham, PhD
Principal Investigator
University of North Carolina, Chapel Hill
Study Contact: 
NamePhoneEmail
Carol L. Cheatham, PhD
704-250-5010
Locations
 
 
ClinicalTrials.gov ID 
Official Title: 
The Effect of Blueberry Consumption on Cognition and Body Composition in Elderly Who Are Experiencing Mild Cognitive Decline
Study Start Date: 
January 2012
Study End Date: 
April 2015
Enrollment: 
132