Alzheimer's Disease Education and Referral Center

Clinical Evaluation of Florbetapir F 18 (18F-AV-45)

Clinical Evaluation of Florbetapir F 18 (18F-AV-45)

Overall Status: 
Recruiting
Brief Description: 

This study is designed to standardize imaging studies using florbetapir F 18 PET to provide information on amyloid burden in subjects participating in other studies, such as longitudinal studies of aging and studies of biomarkers for neurodegenerative diseases.

Patient Qualifications: 
Min AgeMax AgeGenderHealthy Volunteers
18 Years
N/A
Both
Yes
Inclusion Criteria: 

  • At least 18 years of age
  • Ability to tolerate the PET scan procedures

Exclusion Criteria: 

  • Clinically significant hepatic, renal, pulmonary, metabolic, or endocrine conditions
  • Clinically significant cardiovascular disease, such as cardiac surgery or myocardial infarction within the last 4 weeks, unstable angina, significant cardiac arrhythmia or conduction disturbance, uncontrolled high blood pressure
  • History of drug or alcohol abuse within the last year or prior prolonged history of abuse
  • Women of childbearing potential who are not surgically sterile, not refraining from sexual activity or not using reliable methods of contraception; women of childbearing potential must not be pregnant or breastfeeding
  • History of relevant severe drug allergy or hypersensitivity, as determined by investigators
  • Taking of an investigational medication under an FDA IND protocol within the last 30 days
  • Unstable medical comorbidities that pose a potential safety risk to the subject
  • Radiopharmaceutical for imaging or therapy within the past 24 hours prior to the imaging session for this study unless the trial sponsor has approved it

Detailed Description: 

None

Central Contact Information: 

For more information about individual study sites, contact Avid Clinical Operations: call 1-215-298-0700 or e-mail clinicaloperations@avidrp.com.

Locations: 
Map Marker CityStateZip CodeStatusPrimary Contact

Geolocation is 33.4636012, -112.0535987

Site
Phoenix
Arizona
85006
Completed
Name:
Phone:

Geolocation is 33.4636012, -112.0535987

Site
Phoenix
Arizona
85006
Recruiting
Name:
Phone:

Geolocation is 33.612697, -112.280129

Site
Sun City
Arizona
85351
Completed
Name:
Phone:

Geolocation is 38.5449065, -121.7405167

Site
Davis
California
95618
Recruiting
Name:
Phone:

Geolocation is 33.6471239, -117.8421325

Site
Irvine
California
92697
Completed
Name:
Phone:

Geolocation is 34.0502898, -118.2117257

Site
Los Angeles
California
90033
Recruiting
Name:
Phone:

Geolocation is 33.78659, -117.8750976

Site
Orange
California
92868
Recruiting
Name:
Phone:

Geolocation is 37.7813454, -122.497668

Site
San Francisco
California
94121
Recruiting
Name:
Phone:

Geolocation is 37.7642093, -122.4571623

Site
San Francisco
California
94143
Recruiting
Name:
Phone:

Geolocation is 37.7813454, -122.497668

Site
San Francisco
California
94121
Completed
Name:
Phone:

Geolocation is 30.3476884, -81.7458845

Site
Jacksonville
Florida
32254
Recruiting
Name:
Phone:

Geolocation is 25.8176795, -80.1372757

Site
Miami Beach
Florida
33140
Recruiting
Name:
Phone:

Geolocation is 41.8925085, -87.6161696

Site
Chicago
Illinois
60611
Recruiting
Name:
Phone:

Geolocation is 39.06, -94.61

Site
Kansas City
Kansas
66160
Completed
Name:
Phone:

Geolocation is 39.2962372, -76.5928888

Site
Baltimore
Maryland
21287
Completed
Name:
Phone:

Geolocation is 39.2962372, -76.5928888

Site
Baltimore
Maryland
21287
Recruiting
Name:
Phone:

Geolocation is 42.3652917, -71.0646337

Site
Boston
Massachusetts
02114
Recruiting
Name:
Phone:

Geolocation is 32.3361632, -90.1565209

Site
Jackson
Mississippi
39216
Recruiting
Name:
Phone:

Geolocation is 38.6212468, -90.2526163

Site
St. Louis
Missouri
63110
Recruiting
Name:
Phone:

Geolocation is 36.0038131, -78.9387241

Site
Durham
North Carolina
27710
Active, not recruiting
Name:
Phone:

Geolocation is 36.0937141, -80.3268812

Site
Winston-Salem
North Carolina
27104
Completed
Name:
Phone:

Geolocation is 39.9559288, -75.1574567

Site
Philadelphia
Pennsylvania
19107
Not yet recruiting
Name:
Phone:

Geolocation is 41.8396817, -71.3883751

Site
Providence
Rhode Island
02906
Recruiting
Name:
Phone:

Geolocation is 35.9113041, -83.8685072

Site
Knoxville
Tennessee
37920
Completed
Name:
Phone:

Geolocation is 36.1426398, -86.8001068

Site
Nashville
Tennessee
37232
Recruiting
Name:
Phone:

Geolocation is 32.8296623, -96.8511814

Site
Dallas
Texas
75235
Recruiting
Name:
Phone:

Geolocation is 32.8798071, -96.7547522

Site
Dallas
Texas
75231
Recruiting
Name:
Phone:

Geolocation is 32.8113367, -96.8397899

Site
Dallas
Texas
75390
Recruiting
Name:
Phone:
Lead Sponsor: 
Agency
Avid Radiopharmaceuticals
Collaborator Sponsor: 
Facility Investigators: 
NameRoleAffiliation
Chief Medical Officer
Study Director
Avid Radiopharmaceuticals
Study Contact: 
NamePhoneEmail
Avid Clinical Operations
215-298-0700
Locations
 
 
ClinicalTrials.gov ID 
NCT01518374 (follow link to view full record on ct.gov in new window)
Official Title: 
Clinical Evaluation of Florbetapir F 18 (18F-AV-45)
Study Start Date: 
December 2009
Study End Date: 
December 2015
Enrollment: 
600