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Find more clinical trials

Brain Alterations and Cognitive Impairment in Older Adults with Heart Failure

Start: April 2013
End: December 2018
Enrollment: 47

What Is This Study About?

Cognitive impairment is a widely recognized problem in older adults with heart failure, but little is known about specific brain changes in this population. In this observational study, researchers will study the relationship between brain-scan (MRI) results and cognitive impairment in older people with heart failure and without dementia.

Do I Qualify To Participate in This Study?

Minimum Age: 65 Years

Maximum Age: 85 Years

Must have:

  • Diagnosis of heart failure, as defined by New York Heart Association classification I-IV
  • Ability to speak and write in English
  • Stable medication regimen for at least 4 weeks prior to enrollment

Must NOT have:

  • Mini-Mental Status Exam score of 24 or less
  • Current diagnosis of neurological illness or movement disorder (for example, Alzheimer's dementia, Parkinson's disease, epilepsy)
  • History of substance abuse or substance-abuse treatment
  • Untreated depression
  • History of stroke
  • Hepatic insufficiency, severe renal failure, or untreated anemia
  • Left ventricular assist device
  • History of the following within 3 months of study enrollment: acute myocardial infarction, unstable angina, coronary artery bypass surgery, percutaneous transluminal angioplasty, or biventricular pacemaker insertion
  • History of pacemaker, metal implants, or other conditions that would prevent MRI
  • Pregnancy

If I Qualify, Who Do I Contact?

Contact study personnel listed either under the general study contact or the location nearest you.

Need Help?

Contact NIA’s Alzheimer’s and related Dementias Education and Referral (ADEAR) Center at 800-438-4380 or email ADEAR.

Where Is This Study Located?

Who Sponsors This Study?

Lead: University of Wisconsin, Madison

Collaborator Sponsor

  • National Institutes of Health (NIH)

Source: ClinicalTrials.gov ID: NCT01821638

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