Experts Seek Comment on Possible Updates to AD Diagnostic Criteria

July 13, 2010 - Workgroups convened by NIA and the Alzheimer's Association unveiled proposals to update clinical diagnostic criteria for AD and MCI and research criteria for pre-AD and biomarkers in MCI at the 2010 Alzheimer’s Association International Conference on AD. The groups are now seeking comment on the draft criteria. For additional background information: Press release, workgroup panel Q&A 1, workgroup panel Q&A 2

Gene Linked to Alzheimer’s Disease Plays Key Role in Cell Survival

June 10, 2010 -- Scientists have discovered that a gene linked to Alzheimer’s disease may play a beneficial role in cell survival by enabling neurons to clear away toxic proteins. A study funded by the National Institute on Aging (NIA), part of the National Institutes of Health, shows the presenilin 1 (PS1) gene is essential to the function of lysosomes, the cell component that digests and recycles unwanted proteins.

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