Experts Seek Comment on Possible Updates to AD Diagnostic Criteria
July 13, 2010 - Workgroups convened by NIA and the Alzheimer's Association unveiled proposals to update clinical diagnostic criteria for AD and MCI and research criteria for pre-AD and biomarkers in MCI at the 2010 Alzheimer’s Association International Conference on AD. The groups are now seeking comment on the draft criteria. For additional background information: Press release, workgroup panel Q&A 1, workgroup panel Q&A 2

Gene Linked to Alzheimer’s Disease Plays Key Role in Cell Survival
June 10, 2010 -- Scientists have discovered that a gene linked to Alzheimer’s disease may play a beneficial role in cell survival by enabling neurons to clear away toxic proteins. A study funded by the National Institute on Aging (NIA), part of the National Institutes of Health, shows the presenilin 1 (PS1) gene is essential to the function of lysosomes, the cell component that digests and recycles unwanted proteins.

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NIH-Supported Study Looks for Earliest Changes in the Brain That May Lead to Alzheimer’s Disease (press release)
Volunteers with memory problems or concerns are being sought for a clinical study examining the subtle changes that may take place in the brains of older people many years before overt symptoms of Alzheimer’s disease appear. Go to ADNI-GO information or call the ADEAR Center at 1-800-438-4380.

DIAN Study Now Recruiting
The DIAN study is seeking biological adult children of a parent with a mutated gene known to cause dominantly inherited Alzheimer’s disease. Visit the DIAN website or call the ADEAR Center at 1-800-438-4380.

GAP Study Now Recruiting
Volunteers are needed for a new trial of gammaglobulin to reduce brain amyloid in people with Alzheimer’s. Go to GAP study information or call the ADEAR Center at 1-800-438-4380.

Search the AD Clinical Trials database for other studies.

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